2-Ethoxyethanol

2-Ethoxyethanol
Names
	IUPAC name 2-ethoxyethanol
	Other names Cellosolve; ethylene glycol ethyl ether; oxitol; Ethyl Cellosolve; EGEE
Identifiers
CAS Number	110-80-5 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	1098271
ChEBI	CHEBI:46788 ;
ChEMBL	ChEMBL119596 ;
ChemSpider	13836591 ;
DrugBank	DB02249 ;
ECHA InfoCard	100.003.459
EC Number	203-804-1;
Gmelin Reference	82142
KEGG	C14687 ;
PubChem CID	8076;
RTECS number	KK8050000;
UNII	IDK7C2HS09 ;
UN number	1171
CompTox Dashboard (EPA)	DTXSID7024087 ;
	InChI InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3 Key: ZNQVEEAIQZEUHB-UHFFFAOYSA-N; InChI=1/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3 Key: ZNQVEEAIQZEUHB-UHFFFAOYAD;
	SMILES CCOCCO;
Properties
Chemical formula	C4H10O2
Molar mass	90.122 g·mol−1
Appearance	clear liquid
Odor	sweet, ether-like
Density	0.930 g/cm3, liquid
Melting point	−70 °C (−94 °F; 203 K)
Boiling point	135 °C (275 °F; 408 K)
Solubility in water	miscible
Vapor pressure	4 mmHg (20°C)[1]
Hazards
R-phrases (outdated)	R10, R20/21/22,; R60, R61
S-phrases (outdated)	S53, S45
NFPA 704 (fire diamond)	2 2
Flash point	44 °C (111 °F; 317 K)
Explosive limits	1.7%-15.6%[1]
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	2451 mg/kg (mouse, oral); 2125 mg/kg (rat, oral)[2]
LC50 (median concentration)	2000 ppm (rat, 7 hr); 1820 ppm (mouse, 7 hr)[2]
LCLo (lowest published)	3000 ppm (guinea pig, 24 hr)[2]
	NIOSH (US health exposure limits):
PEL (Permissible)	TWA 200 ppm (740 mg/m3) [skin][1]
REL (Recommended)	TWA 0.5 ppm (1.8 mg/m3) [skin][1]
IDLH (Immediate danger)	500 ppm[1]
Related compounds
Related ethers	2-Propoxyethanol; 2-Butoxyethanol
Related compounds	Ethylene glycol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

2-Ethoxyethanol, also known by the trademark Cellosolve or ethyl cellosolve, is a solvent used widely in commercial and industrial applications. It is a clear, colorless, nearly odorless liquid that is miscible with water, ethanol, diethyl ether, acetone, and ethyl acetate.[3]

2-Ethoxyethanol is manufactured by the reaction of ethylene oxide with ethanol.

As with other glycol ethers, 2-ethoxyethanol has the useful property of being able to dissolve chemically diverse compounds. It will dissolve oils, resins, grease, waxes, nitrocellulose, and lacquers.[3] This is an ideal property as a multi-purpose cleaner, and, therefore, 2-ethoxyethanol is used in products such as varnish removers and degreasing solutions.

References

NIOSH Pocket Guide to Chemical Hazards. "#0258". National Institute for Occupational Safety and Health (NIOSH).
"2-Ethoxyethanol". Immediately Dangerous to Life and Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
National Research Council (U.S.). Subcommittee on Spacecraft Maximum Allowable Concentrations (1996). Spacecraft maximum allowable concentrations for selected airborne contaminants. National Academies Press. p. 189. ISBN 978-0-309-05478-2. Retrieved 19 February 2012.

External links

"Chemical Sampling Information 2-Ethoxyethanol". www.osha.gov. Retrieved 4 August 2014.
CDC - NIOSH Pocket Guide to Chemical Hazards

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[PGCH-1] NIOSH Pocket Guide to Chemical Hazards. "#0258". National Institute for Occupational Safety and Health (NIOSH).

[IDLH-2] "2-Ethoxyethanol". Immediately Dangerous to Life and Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).

[Concentrations1996-3] National Research Council (U.S.). Subcommittee on Spacecraft Maximum Allowable Concentrations (1996). Spacecraft maximum allowable concentrations for selected airborne contaminants. National Academies Press. p. 189. ISBN 978-0-309-05478-2. Retrieved 19 February 2012.