23S rRNA (guanine2069-N7)-methyltransferase
23S rRNA (guanine2069-N7)-methyltransferase (EC 2.1.1.264, rlmK (gene), 23S rRNA m7G2069 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine2069-N7)-methyltransferase.[1] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanine2069 in 23S rRNA S-adenosyl-L-homocysteine + N7-methylguanine2069 in 23S rRNA
| 23S rRNA (guanine2069-N7)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.264 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme specifically methylates guanine2069 at position N7 in 23S rRNA.
References
- Kimura S, Ikeuchi Y, Kitahara K, Sakaguchi Y, Suzuki T, Suzuki T (May 2012). "Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity". Nucleic Acids Research. 40 (9): 4071–85. doi:10.1093/nar/gkr1287. PMC 3351187. PMID 22210896.
External links
- 23S+rRNA+(guanine2069-N7)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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