Alkylamidase

In enzymology, an alkylamidase (EC 3.5.1.39) is an enzyme that catalyzes the chemical reaction

N-methylhexanamide + H2O hexanoate + methylamine
alkylamidase
Identifiers
EC number3.5.1.39
CAS number62213-19-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are N-methylhexanamide and H2O, whereas its two products are hexanoate and methylamine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-methylhexanamide amidohydrolase.

References
    • Chen PR, Dauterman WC (1971). "Alkylamidase of sheep liver". Biochim. Biophys. Acta. 250 (1): 216–23. doi:10.1016/0005-2744(71)90137-9. PMID 5141674.


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