Andrea Ablasser

Andrea Ablasser (born 1983) is a German immunologist who works as an associate professor at the École Polytechnique Fédérale de Lausanne. Her research has focused on how the innate immune system is able to recognise virus-infected cells and pathogens.

Andrea Ablasser
Andrea Ablasser in 2014
Born1983 (age 37–38)
Bad Friedrichshall, Heilbronn, Baden-Württemberg, Germany
AwardsJürgen Wehland Prize
Paul Ehrlich Prize for Young Researchers
Academic background
Alma materLudwig Maximilian University of Munich
University of Massachusetts
Harvard Medical School
Academic work
InstitutionsUniversity of Bonn
École Polytechnique Fédérale de Lausanne
Main interestsDNA sensors

Early life and education

Ablasser was born in 1983[1] to a physician father and mathematician mother. She was born in Bad Friedrichshall and moved to Buchloe at the age of three, where her father was the chief physician at the Buchloer Hospital. She attended Gymnasiums in Türkheim and Hohenschwangau, and was inspired by her father to study medicine at the Ludwig Maximilian University of Munich (LMU).[2] She completed part of her studies at the University of Massachusetts and did part of her practical training at Harvard Medical School.[1] When she finished her medical degree in 2008, she was ranked as one of the top ten students in Germany.[3] Although she initially wanted to pursue oncology, she chose to write a doctoral thesis in the field of immunology,[2] and received her doctorate from LMU in 2010.[1]

Career

After completing her doctorate, Ablasser followed her thesis supervisor from LMU to the University of Bonn.[2] She worked at the Institute of Clinical Chemistry and Clinical Pharmacology as the head of a junior research group. Her research focused on DNA sensors that allow the innate immune system to detect whether a cell is infected.[4][5][6] She discovered a novel second messenger molecule that is produced by a particular DNA sensor and "alerts" nearby cells when it encounters a pathogen.[1][7] In 2013, she was awarded the Jürgen Wehland Prize by the Helmholtz Centre for Infection Research for her research on the mechanisms by which the innate immune system recognises pathogens, and specifically her identification of receptors and regulatory molecules that are activated in virally infected cells.[3] In 2014, she won the Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers and the German GlaxoSmithKline Foundation's "Medical Research" Science Award.[8] In 2018 she was awarded the Eppendorf Award for Young European Investigators for her findings in innate immunity.[9] In 2018 she also awarded the European Research Council (ERC) Starting Grant for her project “ImAgine: Exploring the link between innate Immunity and cellular Aging.” Ablasser in her own words says, "With ImAgine we aim to refine our understanding of the molecular connections between innate immunity and cellular senescence with the goal to exploit this knowledge for novel therapeutic strategies.”.[10] In 2019, she was elected as an EMBO member. [11]

Ablasser was appointed as a tenured track assistant professor at the École Polytechnique Fédérale de Lausanne (EPFL) in the university's Global Health Institute in 2014.[12] She has since been promoted to associate professor.

Awards
  • 2014: Paul Ehrlich- and Ludwig Darmstaedter-Nachwuchspreis[13]
  • 2018: Eppendorf Award for Young European Investigators[14]
  • 2018: Swiss Latsis Prize for her work on understanding the immune system.[15]

References
  1. "The immunologist Dr. Andrea Ablasser receives the Paul Ehrlich Prize for Young Researchers" (Press release). Goethe University of Frankfurt. 14 March 2014. Retrieved 9 November 2015.
  2. Utz, Stephanie (24 March 2014). "Kämpferin gegen den Krebs". Augsburger Allgemeine (in German). Retrieved 9 November 2015.
  3. "Andrea Ablasser receives prize for junior scientists". Helmholtz Centre for Infection Research. 24 October 2013. Retrieved 9 November 2015.
  4. "Cell senescence is regulated by innate DNA sensing". ScienceDaily. Retrieved 2018-07-27.
  5. "The STING of death in T cells". ScienceDaily. Retrieved 2018-07-27.
  6. "TB Uses Trickery and Deception to Evade Immune System | GEN". GEN. 2015-06-05. Retrieved 2018-07-27.
  7. "New small molecules pave the way for treating autoinflammatory disease". ScienceDaily. Retrieved 2018-07-27.
  8. "Wissenschaftspreis 2014" (in German). GlaxoSmithKline Stiftung. Retrieved 9 November 2015.
  9. "2018 Eppendorf Award for Young European Investigators Presented to Andrea Ablasser". Technology Networks. Retrieved 2018-07-27.
  10. "Andrea Ablasser wins ERC Starting Grant".
  11. "EMBO elects 56 new members". EMBO. Retrieved 6 August 2020.
  12. "10 Professorinnen und Professoren an den beiden ETH ernannt" (in German). ETH Domain. 7 March 2014. Retrieved 9 November 2015.
  13. "Die Immunologin Andrea Ablasser erhält Paul Ehrlich- und Ludwig Darmstaedter-Nachwuchspreis 2014 - MEDIZIN ASPEKTE". MEDIZIN ASPEKTE (in German). 2014-03-14.
  14. "Andrea Ablasser wins the 2018 Eppendorf Award for Young European Investigators". Retrieved 2018-11-02.
  15. "German scientist awarded Latsis Prize for immune research". SWI swissinfo.ch. 2018-11-01.
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