Bernd Giese

Bernd Giese (born 2 June 1940) is a German chemist and guest professor in chemistry at the University of Fribourg in Fribourg, Switzerland since 2010.[1]

Biography

Born in Hamburg, Germany, Giese received his Ph.D. from the University of Munich under Rolf Huisgen in 1969.[lower-alpha 1] From 1969 to 1971 he worked in pharmaceutical research at BASF in Ludwigshafen. He obtained his Habilitation from the University of Freiburg in 1976. From 1977 to 1988 he was full professor at the Technical University of Darmstadt[2] and from 1989 to 2010 at the University of Basel.[1]

Research

Giese specializes in the bio-organic chemistry and synthesis of radicals in biological systems.[3][4][5] He contributed to the understanding of radical induced DNA cleavage and of the DNA synthesis by ribonucleotide reductase.[6] He discovered that long range charge transfer through DNA and Peptides occurs by a hopping mechanism.[6][7][8] The formation of CC bonds by addition of free radicals to alkenes is called Giese reaction.[9] Giese developed concepts, guidelines, and synthetic applications for the stereochemistry of radical reactions.[10]

Awards

Reuters News agency predicted him as a possible Nobel Laureate in Chemistry in 2009.[4]

Notes
  1. Title of the dissertation: Beiträge zum Mechanismus der Amin-Addition an Acetylen-Carbonester OCLC 62794433

References
  1. ORCID 0000-0002-6975-8608
  2. "curriculum2". www.chemie1.unibas.ch.
  3. Taylor, Peter, ed. (2002). Mechanism and Synthesis. Royal Society of Chemistry. ISBN 978-0-85404-695-9.
  4. "Thomson Reuters Predicts Nobel Laureates". Archived from the original on October 8, 2009. Retrieved November 19, 2009.
  5. "research2". www.chemie1.unibas.ch.
  6. "Bernd Giese". American Academy of Arts and Sciences. Retrieved 13 June 2020.
  7. Giese, Bernd (2000). "Long-Distance Charge Transport in DNA: The Hopping Mechanism". Accounts of Chemical Research. 33 (9): 631–636. doi:10.1021/ar990040b. ISSN 0001-4842. PMID 10995201.
  8. Meggers, Eric; Michel-Beyerle, Maria E.; Giese, Bernd (Dec 1998). "Sequence Dependent Long Range Hole Transport in DNA". Journal of the American Chemical Society. 120 (49): 12950–12955. doi:10.1021/ja983092p. ISSN 0002-7863.
  9. Giese, Bernd (1983). "Formation of CC Bonds by Addition of Free Radicals to Alkenes". Angewandte Chemie International Edition in English. 22 (10): 753–764. doi:10.1002/anie.198307531. ISSN 0570-0833.
  10. Curran, Dennis P.; Porter, Ned A.; Giese, Bernd (1995). Stereochemistry of Radical Reactions: Concepts, Guidelines, and Synthetic Applications. doi:10.1002/9783527615230. ISBN 9783527293728.
  11. "Tetrahedron Prize for Creativity in Organic Chemistry". Elsevier. Archived from the original on 9 September 2014. Retrieved 28 January 2015.
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