CNOT11

CCR4-NOT transcription complex subunit 11 is a protein that in humans is encoded by the CNOT11 gene.[5] It is a subunit of the CCR4-Not deadenylase complex.

CNOT11
Identifiers
Aliases	CNOT11, C2orf29, C40, CCR4-NOT transcription complex subunit 11
External IDs	MGI: 106580 HomoloGene: 9711 GeneCards: CNOT11
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q11.2 Start 101,252,886 bp[1] End 101,270,316 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 B|1 18.31 cM Start 39,534,992 bp[2] End 39,546,889 bp[2]
Gene ontology Molecular function • GO:0001948 protein binding • molecular function Cellular component • cytoplasm • cytosol • cell nucleus • CCR4-NOT complex Biological process • nuclear-transcribed mRNA poly(A) tail shortening • gene silencing by RNA • cellular proliferation • regulation of transcription, DNA-templated • regulation of translation • transcription, DNA-templated • DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55571	52846
Ensembl	ENSG00000158435	ENSMUSG00000003135
UniProt	Q9UKZ1	Q9CWN7
RefSeq (mRNA)	NM_017546	NM_028043
RefSeq (protein)	NP_060016	NP_082319
Location (UCSC)	Chr 2: 101.25 – 101.27 Mb	Chr 1: 39.53 – 39.55 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000158435 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000003135 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: CCR4-NOT transcription complex subunit 11". Retrieved 2020-04-15.

Further reading

• Mauxion F, Prève B, Séraphin B (February 2013). "C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex". RNA Biol. 10 (2): 267–76. doi:10.4161/rna.23065. PMC 3594285. PMID 23232451.