CRELD2

Cysteine-rich with EGF-like domain protein 2 is a protein that in humans is encoded by the CRELD2 gene.[5][6]

CRELD2
Identifiers
Aliases	CRELD2, cysteine rich with EGF like domains 2
External IDs	OMIM: 607171 MGI: 1923987 HomoloGene: 11526 GeneCards: CRELD2
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.33 Start 49,918,167 bp[1] End 49,927,540 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E3 Start 88,819,646 bp[2] End 88,826,683 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	79174	76737
Ensembl	ENSG00000184164	ENSMUSG00000023272
UniProt	Q6UXH1	Q9CYA0
RefSeq (mRNA)	NM_001135101 NM_001284317 NM_001284318 NM_024324	NM_029720
RefSeq (protein)	NP_001128573 NP_001271246 NP_001271247 NP_077300	NP_083996
Location (UCSC)	Chr 22: 49.92 – 49.93 Mb	Chr 15: 88.82 – 88.83 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000184164 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000023272 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Rupp PA, Fouad GT, Egelston CA, Reifsteck CA, Olson SB, Knosp WM, Glanville RW, Thornburg KL, Robinson SW, Maslen CL (Jul 2002). "Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins". Gene. 293 (1–2): 47–57. doi:10.1016/S0378-1119(02)00696-0. PMID 12137942.
6. "Entrez Gene: CRELD2 cysteine-rich with EGF-like domains 2".

External links

• Human CRELD2 genome location and CRELD2 gene details page in the UCSC Genome Browser.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ortiz JA, Castillo M, del Toro ED, et al. (2006). "The cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits". J. Neurochem. 95 (6): 1585–96. doi:10.1111/j.1471-4159.2005.03473.x. PMID 16238698.
• Maslen CL, Babcock D, Redig JK, et al. (2007). "CRELD2: gene mapping, alternate splicing, and comparative genomic identification of the promoter region". Gene. 382: 111–20. doi:10.1016/j.gene.2006.06.016. PMID 16919896.