CSDC2

Cold shock domain-containing protein C2 is a protein that in humans is encoded by the CSDC2 gene.[5][6][7]

CSDC2
Identifiers
Aliases	CSDC2, PIPPIN, dJ347H13.2, cold shock domain containing C2
External IDs	OMIM: 617689 MGI: 2146027 HomoloGene: 8701 GeneCards: CSDC2
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.2 Start 41,561,010 bp[1] End 41,577,741 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E1 Start 81,936,759 bp[2] End 81,950,941 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA binding • GO:0001948 protein binding • RNA binding • nucleic acid binding • mRNA 3'-UTR binding • transcription factor binding Cellular component • cell nucleus • cytoplasm Biological process • mRNA processing • regulation of transcription, DNA-templated • regulation of mRNA stability Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	27254	105859
Ensembl	ENSG00000172346	ENSMUSG00000042109
UniProt	Q9Y534	Q91YQ3
RefSeq (mRNA)	NM_014460	NM_145473
RefSeq (protein)	NP_055275	NP_663448
Location (UCSC)	Chr 22: 41.56 – 41.58 Mb	Chr 15: 81.94 – 81.95 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000172346 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042109 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Castiglia D, Scaturro M, Nastasi T, Cestelli A, Di Liegro I (Mar 1996). "PIPPin, a putative RNA-binding protein specifically expressed in the rat brain". Biochem Biophys Res Commun. 218 (1): 390–4. doi:10.1006/bbrc.1996.0068. PMID 8573167.
6. Raimondi L, D'Asaro M, Proia P, Nastasi T, Di Liegro I (May 2003). "RNA-binding ability of PIPPin requires the entire protein". J Cell Mol Med. 7 (1): 35–42. doi:10.1111/j.1582-4934.2003.tb00200.x. PMC 6740078. PMID 12767259.
7. "Entrez Gene: CSDC2 cold shock domain containing C2, RNA binding".

External links

• Human CSDC2 genome location and CSDC2 gene details page in the UCSC Genome Browser.

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Nastasi T, Scaturro M, Bellafiore M, et al. (1999). "PIPPin is a brain-specific protein that contains a cold-shock domain and binds specifically to H1 degrees and H3.3 mRNAs". J. Biol. Chem. 274 (34): 24087–93. doi:10.1074/jbc.274.34.24087. PMID 10446180.
• Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
• Nastasi T, Muzi P, Beccari S, et al. (2001). "Specific neurons of brain cortex and cerebellum are PIPPin positive". NeuroReport. 11 (10): 2233–6. doi:10.1097/00001756-200007140-00034. PMID 10923677.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Schäfer C, Steffen H, Krzykowski KJ, et al. (2003). "CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells". Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4): G726–34. doi:10.1152/ajpgi.00111.2003. PMID 12801884.
• Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.