Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
In enzymology, a cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase (EC 1.3.1.49) is an enzyme that catalyzes the chemical reaction
- (+)-cis-3,4-dihydrophenanthrene-3,4-diol + NAD+ phenanthrene-3,4-diol + NADH + H+
| cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.49 | ||||||||
| CAS number | 118390-61-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are (+)-cis-3,4-dihydrophenanthrene-3,4-diol and NAD+, whereas its 3 products are phenanthrene-3,4-diol, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase. This enzyme participates in naphthalene and anthracene degradation.
References
- Nagao K, Takizawa N, Kiyahara H (1988). "Purification and properties of cis-phenanthrene dihydrodiol dehydrogenase in Alcaligenes faecalis AFK2". Agric. Biol. Chem. 52 (10): 2621–2623. doi:10.1271/bbb1961.52.2621.
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