DEFB119

Beta-defensin 119 is a protein that in humans is encoded by the DEFB119 gene.[5][6]

DEFB119
Identifiers
Aliases	DEFB119, DEFB-19, DEFB-20, DEFB120, ESC42-RELA, ESC42-RELB, DEFB20, defensin beta 119
External IDs	OMIM: 615997 MGI: 2385955 HomoloGene: 17045 GeneCards: DEFB119
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q11.21 Start 31,377,164 bp[1] End 31,390,590 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 H1 Start 152,576,086 bp[2] End 152,580,312 bp[2]
Gene ontology Molecular function • lipopolysaccharide binding Cellular component • extracellular region • cell surface Biological process • defense response to bacterium • defense response • innate immune system Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	245932	246700
Ensembl	ENSG00000180483	ENSMUSG00000050645
UniProt	Q8N690	Q8K3I8
RefSeq (mRNA)	NM_001271209 NM_153289 NM_153323	NM_145157
RefSeq (protein)	NP_001258138 NP_695021 NP_697018	NP_660139
Location (UCSC)	Chr 20: 31.38 – 31.39 Mb	Chr 2: 152.58 – 152.58 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000180483 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050645 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB Jr (Feb 2002). "Discovery of five conserved beta -defensin gene clusters using a computational search strategy". Proc Natl Acad Sci U S A. 99 (4): 2129–33. doi:10.1073/pnas.042692699. PMC 122330. PMID 11854508.
6. "Entrez Gene: DEFB119 defensin, beta 119".

Further reading

• Lehrer RI, Ganz T (2002). "Defensins of vertebrate animals". Curr. Opin. Immunol. 14 (1): 96–102. doi:10.1016/S0952-7915(01)00303-X. PMID 11790538.
• Raj PA, Dentino AR (2002). "Current status of defensins and their role in innate and adaptive immunity". FEMS Microbiol. Lett. 206 (1): 9–18. doi:10.1111/j.1574-6968.2002.tb10979.x. PMID 11786250.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Yamamoto M, Matsui Y (2003). "Testis-specific expression of a novel mouse defensin-like gene, Tdl". Mech. Dev. 116 (1–2): 217–21. doi:10.1016/S0925-4773(02)00144-2. PMID 12128228.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.