DMTF1

Cyclin-D-binding Myb-like transcription factor 1 is a protein that in humans is encoded by the DMTF1 gene.[5][6]

DMTF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LLK
Identifiers
Aliases	DMTF1, DMP1, DMTF, MRUL, hDMP1, cyclin D binding myb like transcription factor 1
External IDs	OMIM: 608491 MGI: 1344415 HomoloGene: 8017 GeneCards: DMTF1
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.12 Start 87,152,361 bp[1] End 87,196,337 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 A1 Start 9,118,801 bp[2] End 9,161,776 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific Cellular component • nucleoplasm • cytosol • cell nucleus Biological process • cell cycle • regulation of transcription, DNA-templated • transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter • cell differentiation • positive regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9988	23857
Ensembl	ENSG00000135164	ENSMUSG00000042508
UniProt	Q9Y222	Q8CE22
RefSeq (mRNA)	NM_001142326 NM_001142327 NM_021145	NM_001110327 NM_011806
RefSeq (protein)	NP_001135798 NP_001135799 NP_066968	NP_001103797 NP_035936
Location (UCSC)	Chr 7: 87.15 – 87.2 Mb	Chr 5: 9.12 – 9.16 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000135164 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042508 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bodner SM, Naeve CW, Rakestraw KM, Jones BG, Valentine VA, Valentine MB, Luthardt FW, Willman CL, Raimondi SC, Downing JR, Roussel MF, Sherr CJ, Look AT (May 1999). "Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1)". Gene. 229 (1–2): 223–8. doi:10.1016/S0378-1119(98)00591-5. PMID 10095122.
6. "Entrez Gene: DMTF1 cyclin D binding myb-like transcription factor 1".

Further reading

• Försti A, Angelini S, Festa F, et al. (2004). "Single nucleotide polymorphisms in breast cancer". Oncol. Rep. 11 (4): 917–22. doi:10.3892/or.11.4.917. PMID 15010895.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Tschan MP, Fischer KM, Fung VS, et al. (2003). "Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns". J. Biol. Chem. 278 (44): 42750–60. doi:10.1074/jbc.M307067200. PMID 12917399.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• <Please add first missing authors to populate metadata.> (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Inoue K, Sherr CJ, Shapiro LH (1998). "Regulation of the CD13/aminopeptidase N gene by DMP1, a transcription factor antagonized by D-type cyclins". J. Biol. Chem. 273 (44): 29188–94. doi:10.1074/jbc.273.44.29188. PMID 9786929.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Hirai H, Sherr CJ (1996). "Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1". Mol. Cell. Biol. 16 (11): 6457–67. doi:10.1128/MCB.16.11.6457. PMC 231647. PMID 8887674.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.