DNAL4

Dynein light chain 4, axonemal is a protein that in humans is encoded by the DNAL4 gene.[5][6]

DNAL4
Identifiers
Aliases	DNAL4, PIG27, MRMV3, dynein axonemal light chain 4
External IDs	OMIM: 610565 MGI: 1859217 HomoloGene: 38094 GeneCards: DNAL4
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.1 Start 38,778,508 bp[1] End 38,794,198 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 E1|15 37.85 cM Start 79,761,453 bp[2] End 79,777,849 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • cellular motor activity • GO:0001948 protein binding • microtubule motor activity • cytoskeletal protein binding • ATP-dependent microtubule motor activity, plus-end-directed • dynein intermediate chain binding • dynein light intermediate chain binding Cellular component • cytoplasm • cell membrane • cell projection • cilium • microtubules • cytoskeleton • dynein complex Biological process • microtubule-based process • microtubule-based movement • positive regulation of ATP-dependent microtubule motor activity, plus-end-directed Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10126	54152
Ensembl	ENSG00000100246	ENSMUSG00000022420
UniProt	O96015	Q9DCM4
RefSeq (mRNA)	NM_005740	NM_017470
RefSeq (protein)	NP_005731	NP_059498
Location (UCSC)	Chr 22: 38.78 – 38.79 Mb	Chr 15: 79.76 – 79.78 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000100246 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022420 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–495. doi:10.1038/990031. PMID 10591208.
6. "Entrez Gene: DNAL4 dynein, axonemal, light chain 4".

Further reading

• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. doi:10.1038/nature04209. PMID 16189514.
• Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Iwasaki M, Kuwata T, Yamazaki Y, Jenkins NA, Copeland NG, Osato M, Ito Y, Kroon E, Sauvageau G, Nakamura T (2005). "Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model". Blood. 105 (2): 784–793. doi:10.1182/blood-2004-04-1508. PMID 15454493.
• Collins JE, Goward ME, Cole CG, Smink LJ, Huckle EJ, Knowles S, Bye JM, Beare DM, Dunham I (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

External links

• DNAL4 human gene location in the UCSC Genome Browser.
• DNAL4 human gene details in the UCSC Genome Browser.