Dibenzoylhydrazine
Dibenzoylhydrazine (DBH) is a synthetic chemical compound with the chemical formulation C14H12N2O2. It is sometimes known as a benzoic acid amine, and is related to benzoyl peroxide, tricarban, isocarboxazid, and hydrazine. The substance was patented as an "ecdysone receptor ligand-binding domain structure" on 9 December 2004 by Michael C. Lawrence and nine others at the Australian CSIRO,[1] and since 1991 it had been known to be effective in compound form against insect pests of the orders Lepidoptera, Coleoptera, and Hemiptera.[2]
Names | |
---|---|
IUPAC name
N&prime-Benzoylbenzohydrazide | |
Other names
1,2-Dibenzoylhydrazine | |
Identifiers | |
3D model (JSmol) |
|
523810 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.011.209 |
EC Number |
|
281733 | |
PubChem CID |
|
CompTox Dashboard (EPA) |
|
| |
| |
Properties | |
C14H12N2O2 | |
Molar mass | 240.262 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Tebufenozide, methoxyfenozide and halofenozide are classed as commercial DBHs.[3]
In 2013, a compound of the substance was tested with promising results against larvae of Anopheles gambiae, the major vector for human malaria.[3]
References
- "Ecdysone receptor ligand-binding domain structure", WO 2004106374 A1
- "Dibenzoylhydrazine compound and insecticide", JPH03145447A
- "A new dibenzoylhydrazine with insecticidal activity against Anopheles mosquito larvae", Pest Manag Sci. 2013 Jul;69(7):827-33. doi: 10.1002/ps.3441