EPB41L5

Erythrocyte membrane protein band 4.1 like 5 is a protein in humans that is encoded by the EPB41L5 gene.[5]

EPB41L5
Identifiers
Aliases	EPB41L5, BE37, YMO1, YRT, erythrocyte membrane protein band 4.1 like 5, LULU1, LULU
External IDs	OMIM: 611730 MGI: 103006 HomoloGene: 32492 GeneCards: EPB41L5
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q14.2 Start 120,013,077 bp[1] End 120,179,119 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E2.3 Start 119,545,037 bp[2] End 119,649,000 bp[2]
Gene ontology Molecular function • protein domain specific binding • cytoskeletal protein binding • structural constituent of cytoskeleton Cellular component • focal adhesion • adherens junction • cell membrane • ruffle membrane • cell junction • cell leading edge • cytoplasm • cytoskeleton • cell nucleus • cytosol Biological process • cellular response to transforming growth factor beta stimulus • somitogenesis • axial mesoderm development • endoderm development • negative regulation of cell-cell adhesion • embryonic foregut morphogenesis • epithelial cell morphogenesis • positive regulation of cell-matrix adhesion • substrate-dependent cell migration, cell attachment to substrate • neural plate morphogenesis • somite rostral/caudal axis specification • ectoderm development • positive regulation of epithelial cell migration • in utero embryonic development • negative regulation of protein binding • positive regulation of epithelial to mesenchymal transition • regulation of establishment of protein localization • axial mesoderm morphogenesis • epithelial–mesenchymal transition • posttranscriptional regulation of gene expression • unidimensional cell growth • positive regulation of focal adhesion assembly • mesoderm migration involved in gastrulation • positive regulation of protein binding • cell morphogenesis involved in differentiation • mesoderm development • apical constriction • left/right axis specification • actin cytoskeleton organization • paraxial mesoderm development • actomyosin structure organization Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57669	226352
Ensembl	ENSG00000115109	ENSMUSG00000026383
UniProt	Q9HCM4	Q8BGS1
RefSeq (mRNA)	NM_001184937 NM_001184938 NM_001184939 NM_020909 NM_001330307 NM_001330310	NM_001113416 NM_145506
RefSeq (protein)	NP_001171866 NP_001171867 NP_001171868 NP_001317236 NP_001317239 NP_065960	NP_001106887 NP_663481
Location (UCSC)	Chr 2: 120.01 – 120.18 Mb	Chr 1: 119.55 – 119.65 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000115109 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026383 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Erythrocyte membrane protein band 4.1 like 5". Retrieved 2012-04-26.

Further reading

• Gosens I, Sessa A, den Hollander AI, Letteboer SJ, Belloni V, Arends ML, Le Bivic A, Cremers FP, Broccoli V, Roepman R (Nov 2007). "FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex". Experimental Cell Research. 313 (19): 3959–70. doi:10.1016/j.yexcr.2007.08.025. PMID 17920587.