ERMAP

Erythroid membrane-associated protein is a protein that in humans is responsible for the Scianna blood group system, and is encoded by the ERMAP gene.[5][6]

ERMAP
Identifiers
Aliases	ERMAP, BTN5, PRO2801, RD, SC, erythroblast membrane associated protein (Scianna blood group)
External IDs	OMIM: 609017 MGI: 1349816 HomoloGene: 22782 GeneCards: ERMAP
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p34.2 Start 42,817,122 bp[1] End 42,844,991 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 D2.1|4 55.34 cM Start 119,175,457 bp[2] End 119,190,011 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • receptor binding Cellular component • cytoplasm • membrane • integral component of membrane • cell membrane • external side of plasma membrane Biological process • regulation of immune response • T cell receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	114625	27028
Ensembl	ENSG00000164010	ENSMUSG00000028644
UniProt	Q96PL5	Q9JLN5
RefSeq (mRNA)	NM_001017922 NM_018538	NM_013848 NM_001369066
RefSeq (protein)	NP_001017922 NP_061008	NP_038876 NP_001355995
Location (UCSC)	Chr 1: 42.82 – 42.84 Mb	Chr 4: 119.18 – 119.19 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000164010 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028644 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Xu H, Foltz L, Sha Y, Madlansacay MR, Cain C, Lindemann G, Vargas J, Nagy D, Harriman B, Mahoney W, Schueler PA (Sep 2001). "Cloning and characterization of human erythroid membrane-associated protein, human ERMAP". Genomics. 76 (1–3): 2–4. doi:10.1006/geno.2001.6600. PMID 11549310.
6. "Entrez Gene: ERMAP erythroblast membrane-associated protein (Scianna blood group)".

Further reading

• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Flegel WA, Chen Q, Reid ME, et al. (2006). "SCER and SCAN: two novel high-prevalence antigens in the Scianna blood group system". Transfusion. 45 (12): 1940–4. doi:10.1111/j.1537-2995.2005.00646.x. PMID 16371048. S2CID 6030307.
• Hue-Roye K, Chaudhuri A, Velliquette RW, et al. (2005). "STAR: a novel high-prevalence antigen in the Scianna blood group system". Transfusion. 45 (2): 245–7. doi:10.1111/j.1537-2995.2004.04226.x. PMID 15660834. S2CID 782824.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Krause M, Leslie JD, Stewart M, et al. (2004). "Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics". Dev. Cell. 7 (4): 571–83. doi:10.1016/j.devcel.2004.07.024. PMID 15469845.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wagner FF, Poole J, Flegel WA (2003). "Scianna antigens including Rd are expressed by ERMAP". Blood. 101 (2): 752–7. doi:10.1182/blood-2002-07-2064. PMID 12393480.
• Su YY, Gordon CT, Ye TZ, et al. (2003). "Human ERMAP: an erythroid adhesion/receptor transmembrane protein". Blood Cells Mol. Dis. 27 (5): 938–49. doi:10.1006/bcmd.2001.0465. PMID 11783959.
• Lewis M, Kaita H, Philipps S, et al. (1982). "The position of the Radin blood group locus in relation to other chromosome l loci". Ann. Hum. Genet. 44 (Pt 2): 179–84. doi:10.1111/j.1469-1809.1980.tb00956.x. PMID 6459052. S2CID 30044562.
• Lewis M, Kaita H (1980). "Genetic linkage between the Radin and Rh blood group loci". Vox Sang. 37 (5): 286–9. doi:10.1111/j.1423-0410.1979.tb02306.x. PMID 118583. S2CID 31800860.

External links

• Scianna blood group system in the BGMUT blood group antigen gene mutation database