Ependymin

Ependymin is a glycoprotein associated with the consolidation of long-term memory, possibly providing protection from strokes, and contributing to neuronal regeneration.[1] This encoded protein was originally detected in elevated amounts of fluid within the central nervous system of teleost fishes.[2] Along with long-term memory and neuronal regeneration, ependymin has been connected to specific aspects of changes in signaling within nerve cells leading to brain plasticity,[3] as well as behavioral performance in response to environment stress in fishes.[4]

References
  1. Suárez-Castillo; García-Arrarás (2007). "Molecular evolution of the ependymin protein family: a necessary update". BMC Evolutionary Biology. 7: 23. doi:10.1186/1471-2148-7-23. PMC 1805737. PMID 17302986.
  2. SHASHOUA, VICTOR E. (August 1991). "Ependymin, a Brain Extracellular Glycoprotein, and CNS Plasticity". Annals of the New York Academy of Sciences. 627 (1 Activity–Driv): 94–114. Bibcode:1991NYASA.627...94S. doi:10.1111/j.1749-6632.1991.tb25916.x. ISSN 0077-8923. PMID 1831964.
  3. Pradel, Gabriele; Schmidt, Rupert; Schachner, Melitta (2000-06-15). "Involvement of L1.1 in memory consolidation after active avoidance conditioning in zebrafish". Journal of Neurobiology. 43 (4): 389–403. doi:10.1002/1097-4695(20000615)43:4<389::aid-neu7>3.3.co;2-o. ISSN 0022-3034. PMID 10861564.
  4. Tang, Shye-Jye; Sun, Kuang-Hui; Sun, Guang-Huan; Lin, Guang; Lin, Wen-Wen; Chuang, Mei-Jan (1999-09-27). "Cold-induced ependymin expression in zebrafish and carp brain: implications for cold acclimation". FEBS Letters. 459 (1): 95–99. doi:10.1016/s0014-5793(99)01229-6. ISSN 0014-5793. PMID 10508924.


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