Epsiprantel

Epsiprantel (trade name Cestex) is a veterinary drug which is used as an anthelmintic against tapeworms such as Echinococcus granulosus.[2]

Epsiprantel

Clinical data
Trade names	Cestex
Other names	BRL 38705
Routes of administration	By mouth (tablets)
ATCvet code	QP52AA04 (WHO)
Legal status
Legal status	US: ℞-only
Pharmacokinetic data
Bioavailability	Minimal[1]
Identifiers
IUPAC name 2-(Cyclohexylcarbonyl)-2,3,6,7,8,12b-hexahydropyrazino[2,1-a][2]benzazepin-4(1H)-one
CAS Number	98123-83-2
PubChem CID	72026
ChemSpider	65020
UNII	0C1SPQ0FSR
ChEMBL	ChEMBL64979
CompTox Dashboard (EPA)	DTXSID3057858
Chemical and physical data
Formula	C20H26N2O2
Molar mass	326.440 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C4N2C(c1c(cccc1)CCC2)CN(C(=O)C3CCCCC3)C4
InChI InChI=1S/C20H26N2O2/c23-19-14-21(20(24)16-8-2-1-3-9-16)13-18-17-11-5-4-7-15(17)10-6-12-22(18)19/h4-5,7,11,16,18H,1-3,6,8-10,12-14H2 Key:LGUDKOQUWIHXOV-UHFFFAOYSA-N

Indications

It is indicated for the removal of cestodes (tapeworms) in cats (Dipylidium caninum and Taenia taeniaeformis) and dogs (Dipylidium caninum and Taenia pisiformis) 7 weeks of age and older.[1]

References

1. "Cestex (epsiprantel) Veterinary Tablets. Prescribing Information" (PDF). Zoetis Inc. Kalamazoo, MI 49007. Retrieved 2 October 2016.
2. Arru E, Garippa G, Manger BR (November 1990). "Efficacy of epsiprantel against Echinococcus granulosus infections in dogs". Research in Veterinary Science. 49 (3): 378–9. doi:10.1016/0034-5288(90)90080-N. PMID 2267429.