Etanidazole
Etanidazole is a nitroimidazole drug used for its radiosensitizing properties. Administration of etanidazole results in a decrease of glutathione concentration and inhibits glutathione S-transferase.[1] The result is that tissues become more sensitive to the ionizing radiation used in cancer treatment.
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IUPAC name
N-(2-Hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide | |
Identifiers | |
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.164.363 |
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CompTox Dashboard (EPA) |
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Properties | |
C7H10N4O4 | |
Molar mass | 214.181 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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See also
- 18F-EF5, a related nitroimidazole
- Misonidazole
References
- Definition of etanidazole, National Cancer Institute Drug Dictionary.
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