Franz Pfeiffer (physicist)

Franz Pfeiffer (born 25 November 1972 in Kösching, Germany) is a German physicist known for his contributions to the development of Phase-contrast X-ray imaging and its applications in biomedical research.

Research

Pfeiffer contributed to the extension of known imaging modalities such as Differential interference contrast microscopy and Dark-field microscopy to the X-ray regime. In 2006 he demonstrated the feasibility of phase sensitive X-ray imaging with conventional, polychromatic X-ray sources and a grating interferometer.[1] This enlarged the potential of X-ray phase imaging for clinical use as before the technique was only possible at synchrotron facilities. Pfeiffer further introduced the extraction of a supplementary signal (so-called "dark-field signal") sensitive to porous microstructure of a sample based on X-ray scattering.[2] His research group at the Technical University Munich demonstrated a range of possible applications of the new modalities in medical and material research.

Further Pfeiffer is known for his research in X-ray Ptychography,[3] X-ray tensor tomography,[4][5] grating-based Neutron interferometric imaging[6] and iterative CT reconstruction algorithms. He is author and co-author of more than 250[7] scientific publications and inventor in several patents.

In 2011 he was awarded the Leibniz Prize for his achievements in X-ray physics.

References
  1. Pfeiffer, F.; Weitkamp, T.; Bunk, O.; David, C. (2006). "Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources". Nature Physics. 2 (4): 258–261. Bibcode:2006NatPh...2..258P. doi:10.1038/nphys265.
  2. Pfeiffer, F.; Bech, M.; Bunk, O.; Kraft, P.; Eikenberry, E. F.; Brönnimann, C.; Grünzweig, C.; David, C. (2008). "Hard-X-ray dark-field imaging using a grating interferometer". Nature Materials. 7 (2): 134–137. Bibcode:2008NatMa...7..134P. doi:10.1038/nmat2096. PMID 18204454.
  3. Dierolf, Martin; Menzel, Andreas; Thibault, Pierre; Schneider, Philipp; Kewish, Cameron M.; Wepf, Roger; Bunk, Oliver; Pfeiffer, Franz (2010-09-23). "Ptychographic X-ray computed tomography at the nanoscale". Nature. 467 (7314): 436–439. Bibcode:2010Natur.467..436D. doi:10.1038/nature09419. ISSN 0028-0836. PMID 20864997. S2CID 2449015.
  4. Schaff, Florian; Bech, Martin; Zaslansky, Paul; Jud, Christoph; Liebi, Marianne; Guizar-Sicairos, Manuel; Pfeiffer, Franz (2015-11-19). "Six-dimensional real and reciprocal space small-angle X-ray scattering tomography". Nature. 527 (7578): 353–356. Bibcode:2015Natur.527..353S. doi:10.1038/nature16060. ISSN 0028-0836. PMID 26581292. S2CID 4463780.
  5. Seyyedi, Saeed; Wieczorek, Matthias; Pfeffer, Franz; Lasser, Tobias (2018-01-17). "Incorporating a Noise Reduction Technique Into X-Ray Tensor Tomography". IEEE Transactions on Computational Imaging. 4 (1): 137–146. doi:10.1109/TCI.2018.2794740. ISSN 2333-9403. S2CID 46793582.
  6. Pfeiffer, F.; Grünzweig, C.; Bunk, O.; Frei, G.; Lehmann, E.; David, C. (2006-06-02). "Neutron Phase Imaging and Tomography". Physical Review Letters. 96 (21): 215505. Bibcode:2006PhRvL..96u5505P. doi:10.1103/PhysRevLett.96.215505. PMID 16803249.
  7. "Chair of Biomedical Physics: Franz Pfeiffer". www.e17.ph.tum.de. Retrieved 2017-05-27.


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