Hyperkatifeia

Hyperkatifeia is defined as hypersensitivity to emotional distress in the context of opioid abuse.[1]

Hyperkatifeia and Opioid-induced hyperalgesia can be seen with long-term use of illicit street opioids e.g. heroin and prescription opioids e.g. hydrocodone and oxycodone during withdrawal.

References
  1. Shurman J, Koob GF, Gutstein HB (2010). "Opioids, pain, the brain, and hyperkatifeia: a framework for the rational use of opioids for pain". Pain Med. 11 (7): 1092–8. doi:10.1111/j.1526-4637.2010.00881.x. PMC 2907890. PMID 20545871.


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