Igor Larrosa

Igor Guerrero Larrosa is a Spanish chemist and a Professor in the Department of Chemistry at The University of Manchester.[2] His research in general is based on organic chemistry and inorganic chemistry, specifically on the areas of inorganic catalysis and organic synthesis including the application to C-H and decarboxylative activation.[7]

Igor Larrosa
Born
Igor Guerrero Larrosa

1976/1977 (age 43–44)[1]
Barcelona, Spain
Alma materUniversity of Barcelona[2] (Bsc., MSc., PhD)
Known forOrganic synthesis
Catalysis
Awards
Scientific career
FieldsOrganic Chemistry
Inorganic Chemistry
InstitutionsUniversity of Manchester
ThesisReacciones de c-glicosidación estereoselectivas con enolatos de titanio quirales. Síntesis del fragmento c1-c9 de la salinomicina (2004)
Doctoral advisorDr. Fèlix Urpí Tubella
Dr. Pedro Romea García

Education

Larrosa completed his Bachelor of Science degree in 1999 at University of Barcelona. He continued to read for his Master of Science and Doctor of Philosophy at University of Barcelona under the supervision of Dr. Fèlix Urpí Tubella and Dr. Pedro Romea García and successfully completed his PhD in 2004.[8]

Research and career

Upon completing his PhD, Larrosa received a three months fellowship from the Ministry of Education and Science, Spain to work with Prof.Erick M. Carreira at ETH Zürich before moving to Imperial College London for a postdoctoral research with Prof. Anthony Barrett.[2] He then moved to Queen Mary University of London as a Lecturer and was promoted to the position of Senior Lecturer and Reader in 2011 and 2012 respectively. In 2014, he moved to The University of Manchester as a Professor of organic chemistry.[9]

Larrosa's research in general is based on organic chemistry and inorganic chemistry, specifically on the areas of inorganic catalysis and organic synthesis including the application to C-H and decarboxylative activation.[7]

Larrosa received an EPSRC in 2011 and currently holds an EPSRC Advanced Grant.[10] He is also a member of 2D, a research programme in the aim of bringing together a team of multi-disciplinary researchers as well as world-leaders in G2D research.[11]

Notable work

Larrosa is considered as one of the world's leading researcher's in Carbon–hydrogen bond activation.[4][12] C - H bonds in organic compounds are particularly un-reactive due to the strong bonds between the carbon and hydrogen atoms and such bond activation would increase the reactivity and therefore enable the potential development of new novel organic compounds. Larrosa's research has showed how transition metal catalysis maybe used to achieve C - H bond activation,[13][14] and for his efforts in the field, was awarded the Corday-Morgan Prize[3] and was a finalist at the Blavatnik Awards (UK)[4] in 2019. The published research also have shown the enhanced regioselectivity and stereoselectivity in these catalysis processes, which is generally difficult to be achieved in this field.[4] Apart from research based on C - H bond activation, Larrosa has also published several research on decarboxylation and arylation reactions.[15][16]

Awards and Nominations

Major Publications
  • Larrosa, Igor; Righi, Marika; Cornella, Josep (2011). "Carboxylic Acids as Traceless Directing Groups for Formal meta ‐Selective Direct Arylation". Angew. Chem. Int. Ed. 50 (40): 9429–9432. doi:10.1002/anie.201103720. PMID 21948440. Retrieved 17 June 2020.
  • Larrosa, Igor; Boorman, Tanya C. (2011). "Gold-mediated C–H bond functionalisation". Chem. Soc. Rev. 40 (4): 1910–1925. doi:10.1039/C0CS00098A. PMID 21103517. Retrieved 17 June 2020.
  • Larrosa, Igor; Lu, Pengfei; Josep (2009). "Intermolecular Decarboxylative Direct C-3 Arylation of Indoles with Benzoic Acids". Org. Lett. 11 (23): 5506–5509. doi:10.1021/ol902304n. PMID 19877661. Retrieved 17 June 2020.
  • Larrosa, Igor; Lebrasseur, Nathalie (2008). "Room Temperature and Phosphine Free Palladium Catalyzed Direct C-2 Arylation of Indoles". J. Am. Chem. Soc. 130 (10): 2926–2927. doi:10.1021/ja710731a. PMID 18278918. Retrieved 17 June 2020.
  • Larrosa, Igor; Cornella, Josep (2012). "Decarboxylative Carbon-Carbon Bond-Forming Transformations of (Hetero)aromatic Carboxylic Acids" (PDF). Synthesis. 44 (5): 5110–5148. doi:10.1055/s-0031-1289686. Retrieved 17 June 2020.

References
  1. University of Manchester. "Professor Igor Larrosa reaches final of Blavatnik Awards UK". Retrieved 17 June 2020.
  2. University of Manchester. "Prof. Igor Larrosa". Retrieved 17 June 2020.
  3. Royal Society of Chemistry. "2019 Corday-Morgan Prize". Retrieved 17 June 2020.
  4. Blavatnik Awards for Young Scientists. "Igor Larrosa 2019 UK Award Finalist - Faculty". Retrieved 17 June 2020.
  5. Queen Mary University of London. "Queen Mary University of London Science and Engineering News". Retrieved 17 June 2020.
  6. Thieme Chemistry Journal Awards. "Thieme Chemistry Journal Awards and Previous Winners". Retrieved 17 June 2020.
  7. "Igor Larrosa (Google Scholar)". Retrieved 17 June 2020.
  8. Larrosa, Igor G. (2004). Reacciones de c-glicosidación estereoselectivas con enolatos de titanio quirales. Síntesis del fragmento c1-c9 de la salinomicina (PhD thesis) (in Spanish). (subscription required)
  9. Sci-Tron. "Dr Richard Winpenny FRSC FLSW". Retrieved 13 June 2020.
  10. Royal Society of Chemistry. "2019 Corday-Morgan Prize Winner". Retrieved 17 June 2020.
  11. Project 2D. "Project 2D". Retrieved 17 June 2020.
  12. University of Manchester. "Professor Igor Larrosa reaches final of the Blavatnik Awards UK". Retrieved 17 June 2020.
  13. Larrosa, Igor; Boorman, Tanya C. (2011). "Gold-mediated C–H bond functionalisation". Chem. Soc. Rev. 40 (4): 1910–1925. doi:10.1039/C0CS00098A. PMID 21103517. Retrieved 17 June 2020.
  14. Larrosa, Igor; Cambeiro, Xacobe C.; Ahlsten, Nanna (2015). "Au-Catalyzed Cross-Coupling of Arenes via Double C–H Activation". J. Am. Chem. Soc. 137 (50): 15636–15639. doi:10.1021/jacs.5b10593. PMID 26645996. Retrieved 17 June 2020.
  15. Larrosa, Igor; Lebrasseur, Nathalie (2008). "Room Temperature and Phosphine Free Palladium Catalyzed Direct C-2 Arylation of Indoles". J. Am. Chem. Soc. 130 (10): 2926–2927. doi:10.1021/ja710731a. PMID 18278918. Retrieved 17 June 2020.
  16. Larrosa, Igor; Lu, Pengfei; Josep (2009). "Intermolecular Decarboxylative Direct C-3 Arylation of Indoles with Benzoic Acids". Org. Lett. 11 (23): 5506–5509. doi:10.1021/ol902304n. PMID 19877661. Retrieved 17 June 2020.
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