Insulin like 6

Insulin like 6 is a protein that in humans is encoded by the INSL6 gene. [5]

INSL6
Identifiers
Aliases	INSL6, RIF1, insulin like 6
External IDs	OMIM: 606414 MGI: 1351595 HomoloGene: 5197 GeneCards: INSL6
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9p24.1 Start 5,123,880 bp[1] End 5,185,647 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C1 Start 29,321,344 bp[2] End 29,325,356 bp[2]
Gene ontology Molecular function • hormone activity Cellular component • extracellular region • cellular component Biological process • regulation of receptor activity • biological process • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	11172	27356
Ensembl	ENSG00000120210	ENSMUSG00000050957
UniProt	Q9Y581	Q9QY05
RefSeq (mRNA)	NM_007179	NM_013754
RefSeq (protein)	NP_009110	NP_038782
Location (UCSC)	Chr 9: 5.12 – 5.19 Mb	Chr 19: 29.32 – 29.33 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Function

The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization.

References

1. GRCh38: Ensembl release 89: ENSG00000120210 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050957 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Insulin like 6". Retrieved 2016-02-25.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.