Integrated DNA Technologies

Integrated DNA Technologies, Inc. (IDT), headquartered in Coralville, Iowa, is a supplier of custom nucleic acids, serving the areas of academic research, biotechnology, clinical diagnostics, and pharmaceutical development. IDT's primary business is the manufacturing of custom DNA and RNA oligonucleotides (oligos) for research applications.

Integrated DNA
Technologies, Inc.
TypePrivate
IndustryBiotechnology
FoundedCoralville, IA, USA 1987
FounderDr. Joseph A. Walder
Headquarters
Coralville, IA
,
U.S.
Number of locations
Coralville, IA USA - San Diego, CA USA - Skokie, IL USA - Leuven, Belgium - Singapore
Area served
Research and diagnostics life sciences market
ProductsOligonucleotides
WebsiteIDTDNA.com

Joseph A. Walder, M.D., Ph.D. (Northwestern University), founded Integrated DNA Technologies, Inc. in 1987 through a partnership with Baxter Healthcare Corporation at the University of Iowa Technology Innovation Center business incubator. In its first 10 years, IDT grew from a startup with 10 synthesizing machines to a small company with more than 500, shipping an average 75,000 custom oligos per day to more than 82,000 customers worldwide. In March 2018, IDT was acquired by Danaher Corporation for a reported $1.9 billion. [1]

Mission

IDT's mission is to enable discovery in biology and medicine. The company strives to achieve this by improving nucleic acid synthesis technology and developing new applications for the use of DNA- and RNA-based compounds. IDT's advanced synthesis group combines expertise in chemistry, molecular biology, and engineering to produce and purify complex nucleic acids of all kinds.[2]

SciTools

Synthetic oligonucleotides are used in various molecular biology applications, e.g., polymerase chain reaction (PCR), molecular beacons, microarrays, mutagenesis, RNAi, antisense and gene synthesis. Published bioinformatics algorithms can predict biophysical properties of oligonucleotides from their sequence and estimate oligonucleotide performance in specific assays, when used singly or together with other sequences. IDT's SciTools is a free online suite of computational software tools that enable molecular biologists to design, evaluate and make informed decisions about the properties of nucleic acid sequences. Instructions and help to each software tool can be found at the top of web input forms. The code is regularly updated when more accurate models and algorithms are published.[3]

Major product areas
DNA & RNA Synthesis Oligonucleotide Modifications
Functional Genomics Genotyping
Next Generation Sequencing Gene Expression
Reagents Mutation Detection
GMP for Molecular Diagnostics Large Scale Oligo Synthesis
RNase H-dependent PCR (rhPCR)

Certifications

IDT earned its ISO 9001:2000 certification at its oligonucleotide production headquarters in 2005.[4]

IDT earned its ISO 13485:2003 certification for its Quality Management System in 2008.[5]

References
  1. Reisch, Marc S. (March 19, 2018). "Danaher buys oligonucleotide maker Integrated DNA Technologies". Chemical & Engineering News. Vol. 96 no. 12. p. 10. Archived from the original on 2019-08-09. Retrieved 2020-04-27.
  2. "Archived copy". Archived from the original on 2008-11-21. Retrieved 2008-08-27.CS1 maint: archived copy as title (link)
  3. Owczarzy R, Tataurov AV, Wu Y, et al. (July 2008). "IDT SciTools: a suite for analysis and design of nucleic acid oligomers". Nucleic Acids Res. 36 (Web Server issue): W163–9. doi:10.1093/nar/gkn198. PMC 2447751. PMID 18440976.
  4. "Integrated DNA Technologies". Idtdna.com. Retrieved 2 June 2019.
  5. "Archived copy" (PDF). Archived from the original (PDF) on 2008-12-21. Retrieved 2008-09-02.CS1 maint: archived copy as title (link)
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