Intraepithelial neoplasia
Intraepithelial neoplasia (IEN) is the development of a benign neoplasia or high-grade dysplasia in an epithelium. The exact dividing line between dysplasia and neoplasia has been very difficult to draw throughout the era of medical science. It varies between persons. In the localizations shown below, the term intraepithelial neoplasia is used to describe more accurately what was historically referred to as epithelial dysplasia. IEN is not cancer, but it is associated with higher risk for developing cancer in future. It is thus sometimes a precancerous condition.
High grade anal intraepithelial neoplasia.
Localizations
| Localization | Usual acronym |
|---|---|
| anal intraepithelial neoplasia | AIN |
| biliary intraepithelial neoplasia | BILIN |
| cervical intraepithelial neoplasia | CIN |
| endometrial intraepithelial neoplasia | EIN |
| gastrointestinal intraepithelial neoplasia[1] | GIN |
| pancreatic intraepithelial neoplasia | PanIN |
| penile intraepithelial neoplasia | PEIN |
| prostatic intraepithelial neoplasia | PIN |
| vaginal intraepithelial neoplasia | VIN |
| vulvar intraepithelial neoplasia | VIN |
References
- Schlemper, RJ; et al. (2000). "The Vienna classification of gastrointestinal epithelial neoplasia". Gut. 47 (2): 251–5. doi:10.1136/gut.47.2.251. PMC 1728018. PMID 10896917.
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