Irvine–Gass syndrome

Irvine–Gass syndrome, pseudophakic cystoid macular edema or postcataract CME is one of the most common causes of visual loss after cataract surgery.[1][2] The syndrome is named in honor of S. Rodman Irvine[3][4] and J. Donald M. Gass.[5]

Irvine–Gass Syndrome
Other namesPseudophakic cystoid macular edema, Postcataract CME
SpecialtyOphthalmology

The incidence is more common in older types of cataract surgery, where postcataract CME could occur in 20–60% of patients,[6] but with modern cataract surgery, incidence of Irvine–Gass syndrome have reduced significantly.[7]

Replacement of the lens as treatment for cataract can cause pseudophakic macular edema. (‘pseudophakia’ means ‘replacement lens’) this could occur as the surgery involved sometimes irritates the retina (and other parts of the eye) causing the capillaries in the retina to dilate and leak fluid into the retina. This is less common today with modern lens replacement techniques.[8]

References
  1. Flach, A J (1998). "The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery". Trans Am Ophthalmol Soc. 96: 557–634. PMC 1298410. PMID 10360304.
  2. Kiernan, Daniel F.; Hariprasad, Seenu M. (1 November 2013). "Controversies in the management of Irvine–Gass syndrome". Ophthalmic Surgery, Lasers and Imaging Retina. 44 (6): 522–527. doi:10.3928/23258160-20131105-01. PMID 24221459.
  3. Straatsma, Bradley R. (2000). "S. Rodman Irvine, MD". Transactions of the American Ophthalmological Society. 98: 9–10. PMC 1298207.
  4. Irvine, Alexander (2000). "S. Rodman Irvine, MD (1906–1999". Archives of Ophthalmology. 118 (6): 863. doi:10.1001/archopht.118.6.863.
  5. Flynn, Harry W.; Curtin, Victor T. (2005). "J. Donald M. Gass, MD (1928–2005)". Archives of Ophthalmology. 123 (7): 1023. doi:10.1001/archopht.123.7.1023.
  6. Telander, David G; Cessna, Christopher T (2019-10-20). "Pseudophakic (Irvine–Gass) Macular Edema". Medscape.
  7. Bélair, Marie-Lyne; Kim, Stephen J.; Thorne, Jennifer E.; Dunn, James P.; Kedhar, Sanjay R.; Brown, Diane M.; Jabs, Douglas A. (July 2009). "Incidence of Cystoid Macular Edema after Cataract Surgery in Patients with and without Uveitis Using Optical Coherence Tomography". American Journal of Ophthalmology. 148 (1): 128–135.e2. doi:10.1016/j.ajo.2009.02.029. PMC 2722753. PMID 19403110.
  8. Boston, David R. Lally, MD, and Chirag P. Shah, MD, MPH. "Pseudophakic Cystoid Macular Edema". Retrieved 2017-12-13.
Classification
External resources


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