JAKMIP2

Janus kinase and microtubule interacting protein 2 is a protein that in humans is encoded by the JAKMIP2 gene. [5]

JAKMIP2
Identifiers
Aliases	JAKMIP2, JAMIP2, NECC1, janus kinase and microtubule interacting protein 2
External IDs	OMIM: 611197 MGI: 1923467 HomoloGene: 8866 GeneCards: JAKMIP2
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q32 Start 147,585,438 bp[1] End 147,782,775 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 B3 Start 43,531,407 bp[2] End 43,687,773 bp[2]
Orthologs
Species	Human	Mouse
Entrez	9832	76217
Ensembl	ENSG00000176049	ENSMUSG00000024502
UniProt	Q96AA8	D3YXK0
RefSeq (mRNA)	NM_014790 NM_001270934 NM_001270941 NM_001282282	NM_001163637
RefSeq (protein)	NP_001257863 NP_001257870 NP_001269211 NP_055605	NP_001157109
Location (UCSC)	Chr 5: 147.59 – 147.78 Mb	Chr 18: 43.53 – 43.69 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Function

The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants.

References

1. GRCh38: Ensembl release 89: ENSG00000176049 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000024502 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Janus kinase and microtubule interacting protein 2". Retrieved 2017-05-31.

Further reading

• Cruz-Garcia D, Vazquez-Martinez R, Peinado JR, Anouar Y, Tonon MC, Vaudry H, Castaño JP, Malagon MM (2007). "Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins". FEBS Lett. 581 (17): 3149–56. doi:10.1016/j.febslet.2007.06.002. PMID 17572408. S2CID 29349416.
• Koskinen LL, Einarsdottir E, Korponay-Szabo IR, Kurppa K, Kaukinen K, Sistonen P, Pocsai Z, Széles G, Adány R, Mäki M, Kere J, Saavalainen P (2009). "Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations". Tissue Antigens. 74 (5): 408–16. doi:10.1111/j.1399-0039.2009.01359.x. PMID 19845895.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.