KYAT3

Kynurenine aminotransferase 3 is an enzyme that in humans is encoded by the KYAT3 gene. It is one of the Kynurenine—oxoglutarate transaminases.

KYAT3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ZJG, 3E2F, 3E2Y, 3E2Z
Identifiers
Aliases	KYAT3, KAT3, KATIII, CCBL2, kynurenine aminotransferase 3
External IDs	OMIM: 610656 MGI: 2677849 HomoloGene: 2994 GeneCards: KYAT3
EC number	2.6.1.63
Gene location (Mouse) Chr. Chromosome 3 (mouse)[1] Band 3|3 H1 Start 142,701,051 bp[1] End 142,746,870 bp[1]
Gene ontology Molecular function • cysteine-S-conjugate beta-lyase activity • transaminase activity • kynurenine-oxoglutarate transaminase activity • catalytic activity • lyase activity • pyridoxal phosphate binding • protein homodimerization activity • kynurenine-glyoxylate transaminase activity • transferase activity • RNA binding • kynurenine aminotransferase activity Cellular component • mitochondrion • cytoplasm Biological process • L-kynurenine metabolic process • biosynthetic process • kynurenine metabolic process • cellular amino acid metabolic process • 2-oxoglutarate metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	56267	229905
Ensembl	ENSG00000137944	ENSMUSG00000040213
UniProt	Q6YP21	Q71RI9
RefSeq (mRNA)	NM_001008662 NM_001008661	NM_001293560 NM_173763
RefSeq (protein)	NP_001008661 NP_001008662 NP_001336376 NP_001336377 NP_001336378 NP_001336379	NP_001280489 NP_776124
Location (UCSC)	n/a	Chr 3: 142.7 – 142.75 Mb
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCm38: Ensembl release 89: ENSMUSG00000040213 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.