Kakugo virus
Kakugo virus is a picorna-like virus most commonly found in the brains of worker bees. It is a subtype of the Deformed wing virus.[1] The Kakugo (Japanese for 'ready to attack') virus, when resident in a bee's brain, can contribute to aggressive behaviors similar to those preeminent during a bee's guard phase in their life cycle. Kakugo is the first virus to have been found to cause aggressive behavior, although because the virus was only recently discovered to have such effects, research into the matter is limited.
| Kakugo virus | |
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| Group: | Group IV ((+)ssRNA) |
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| Variety: | Kakugo virus |
Analysis
Kakugo RNA encodes a protein of 2,893 amino acid residues that shares structural features and sequence similarities with various picorna-like virus polyproteins, especially those from sacbrood virus, which infects honeybees. The Kakugo protein contains several domains that correspond to the virion protein, helicase, protease, and RNA-dependent RNA polymerase domains of various picorna-like virus polyproteins.
References
- "Iflaviridae - Positive Sense RNA Viruses". International Committee on Taxonomy of Viruses (ICTV). Retrieved 1 August 2020.
- Holzman, David (March 2004). "Novel Virus May Contribute to Aggressive Behaviors of Bees". Microbe Magazine.
- Fujiyuki, Tomoko; Takeuchi, Hideaki; Ono, Masato; Ohka, Seii; Sasaki, Tetsuhiko; Nomoto, Akio; Kubo, Takeo (February 2004). "Novel insect picorna-like virus identified in the brains of aggressive worker honeybees". Journal of Virology. 78 (3): 1093–100. doi:10.1128/jvi.78.3.1093-1100.2004. PMC 321398. PMID 14722264.