LETMD1

LETM1 domain-containing protein 1 is a protein that in humans is encoded by the LETMD1 gene.[4][5][6]

LETMD1
Identifiers
Aliases	LETMD1, 1110019O13Rik, HCCR-1, HCCR-2, HCCR1, HCRR-2, LETM1 domain containing 1
External IDs	MGI: 1915864 HomoloGene: 9128 GeneCards: LETMD1
Gene location (Mouse) Chr. Chromosome 15 (mouse)[1] Band 15|15 F1 Start 100,469,023 bp[1] End 100,479,164 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • ribosome binding Cellular component • mitochondrial outer membrane • membrane • integral component of membrane • nucleoplasm • mitochondrion • mitochondrial inner membrane Biological process • cellular metal ion homeostasis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	25875	68614
Ensembl	ENSG00000050426	ENSMUSG00000037353
UniProt	Q6P1Q0	Q924L1
RefSeq (mRNA)	NM_001024668 NM_001024669 NM_001024670 NM_001024671 NM_001243689 NM_001300765 NM_015416	NM_134093 NM_001357982 NM_001357983 NM_001357984
RefSeq (protein)	NP_001230618 NP_001287694 NP_056231 NP_001338242 NP_001338245 NP_001338246 NP_001338248 NP_001338249 NP_001338250 NP_001338251 NP_001338252 NP_001338253 NP_001338254 NP_001338255 NP_001338256 NP_001338257 NP_001338259 NP_001338261 NP_001338262 NP_001338263 NP_001338264 NP_001338265 NP_001338266 NP_001338241 NP_001338244	NP_598854 NP_001344911 NP_001344912 NP_001344913
Location (UCSC)	n/a	Chr 15: 100.47 – 100.48 Mb
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCm38: Ensembl release 89: ENSMUSG00000037353 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Ko J, Lee YH, Hwang SY, Lee YS, Shin SM, Hwang JH, Kim J, Kim YW, Jang SW, Ryoo ZY, Kim IK, Namkoong SE, Kim JW (Jul 2003). "Identification and differential expression of novel human cervical cancer oncogene HCCR-2 in human cancers and its involvement in p53 stabilization". Oncogene. 22 (30): 4679–4689. doi:10.1038/sj.onc.1206624. PMID 12879013.
5. Qi ZY, Li Y, Ying K, Wu CQ, Tang R, Zhou ZX, Chen ZP, Hui GZ, Xie Y (Jun 2002). "Isolation of novel differentially expressed genes related to human glioma using cDNA microarray and characterizations of two novel full-length genes". J Neurooncol. 56 (3): 197–208. doi:10.1023/A:1015079705841. PMID 12061725. S2CID 23878825.
6. "Entrez Gene: LETMD1 LETM1 domain containing 1".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ko J, Shin SM, Oh YM, et al. (2004). "Transgenic mouse model for breast cancer: induction of breast cancer in novel oncogene HCCR-2 transgenic mice". Oncogene. 23 (10): 1950–1953. doi:10.1038/sj.onc.1207356. PMID 14691448.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Jung SS, Park HS, Lee IJ, et al. (2006). "The HCCR oncoprotein as a biomarker for human breast cancer". Clin. Cancer Res. 11 (21): 7700–7708. doi:10.1158/1078-0432.CCR-04-2609. PMID 16278390.
• Cho GW, Shin SM, Namkoong H, et al. (2007). "The phosphatidylinositol 3-kinase/Akt pathway regulates the HCCR-1 oncogene expression". Gene. 384: 18–26. doi:10.1016/j.gene.2006.07.006. PMID 16949218.