Linoleate isomerase
In enzymology, a linoleate isomerase (EC 5.2.1.5) is an enzyme that catalyzes the chemical reaction
- 9-cis,12-cis-octadecadienoate 9-cis,11-trans-octadecadienoate
| linoleate isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.2.1.5 | ||||||||
| CAS number | 37318-41-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, 9-cis,12-cis-octadecadienoate, and one product, 9-cis,11-trans-octadecadienoate.
This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is linoleate Delta12-cis-Delta11-trans-isomerase. This enzyme is also called linoleic acid isomerase. This enzyme participates in linoleic acid metabolism.
References
- Kepler CR, Tove SB (1967). "Biohydrogenation of unsaturated fatty acids. 3. Purification and properties of a linoleate delta-12-cis, delta-11-trans-isomerase from Butyrivibrio fibrisolvens". J. Biol. Chem. 242 (24): 5686–92. PMID 5633396.
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