MAGEH1

Melanoma-associated antigen H1 is a protein that in humans is encoded by the MAGEH1 gene.[5][6][7]

MAGEH1
Identifiers
Aliases	MAGEH1, APR-1, APR1, MAGEH, MAGE family member H1
External IDs	OMIM: 300548 MGI: 1922875 HomoloGene: 8545 GeneCards: MAGEH1
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.21 Start 55,452,127 bp[1] End 55,453,566 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X F3 Start 153,036,166 bp[2] End 153,037,575 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cytoplasm Biological process • apoptotic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	28986	75625
Ensembl	ENSG00000187601	ENSMUSG00000047238
UniProt	Q9H213	Q9NWG9
RefSeq (mRNA)	NM_014061	NM_023788
RefSeq (protein)	NP_054780	NP_076277
Location (UCSC)	Chr X: 55.45 – 55.45 Mb	Chr X: 153.04 – 153.04 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This gene is thought to be involved in apoptosis. Multiple polyadenylation sites have been found for this gene.[7]

Interactions

MAGEH1 has been shown to interact with Low affinity nerve growth factor receptor.[5]

References

1. GRCh38: Ensembl release 89: ENSG00000187601 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047238 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Tcherpakov M, Bronfman FC, Conticello SG, Vaskovsky A, Levy Z, Niinobe M, Yoshikawa K, Arenas E, Fainzilber M (Dec 2002). "The p75 neurotrophin receptor interacts with multiple MAGE proteins". J Biol Chem. 277 (51): 49101–4. doi:10.1074/jbc.C200533200. PMID 12414813.
6. Lucas S, De Smet C, Arden KC, Viars CS, Lethe B, Lurquin C, Boon T (Mar 1998). "Identification of a new MAGE gene with tumor-specific expression by representational difference analysis". Cancer Res. 58 (4): 743–52. PMID 9485030.
7. "Entrez Gene: MAGEH1 melanoma antigen family H, 1".

Further reading

• Zhu F, Yan W, Zhao ZL, et al. (2001). "Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes". BioTechniques. 29 (2): 310–3. doi:10.2144/00292st06. PMID 10948432.
• Chomez P, De Backer O, Bertrand M, et al. (2001). "An overview of the MAGE gene family with the identification of all human members of the family". Cancer Res. 61 (14): 5544–51. PMID 11454705.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Fu H, Yang G, Lu F, et al. (2006). "Transcriptional up-regulation of restin by all-trans retinoic acid through STAT1 in cancer cell differentiation process". Biochem. Biophys. Res. Commun. 343 (4): 1009–16. doi:10.1016/j.bbrc.2006.02.176. PMID 16574066.