MINDY4

MINDY lysine 48 deubiquitinase 4, also known as MINDY4, is a human gene.[5]

MINDY4
Identifiers
Aliases	MINDY4, C7orf67, FAM188B, family with sequence similarity 188 member B, MINDY lysine 48 deubiquitinase 4, AQP1, CHIP28, AQP-1
External IDs	MGI: 3583959 HomoloGene: 49991 GeneCards: MINDY4
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p14.3 Start 30,771,417 bp[1] End 30,892,387 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B3 Start 55,203,383 bp[2] End 55,320,222 bp[2]
Orthologs
Species	Human	Mouse
Entrez	84182	330323
Ensembl	ENSG00000106125	ENSMUSG00000038022
UniProt	Q4G0A6	Q3UQI9
RefSeq (mRNA)	NM_032222	NM_001142781 NM_177883
RefSeq (protein)	NP_115598	NP_001136253 NP_808551
Location (UCSC)	Chr 7: 30.77 – 30.89 Mb	Chr 6: 55.2 – 55.32 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Predictions

The predicted molecular weight is 84,400 Daltons and pI is 6.465. pTARGET predicts the cellular location to be in the golgi apparatus with 93.9% confidence.[6]

Expression

Based on the human tissue Gene Expression Omnibus profile, C7orf67 shows a marked increase in expression in the teratospermia disease state.[7]

References

1. GRCh38: Ensembl release 89: ENSG00000106125 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038022 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: C7orf67 chromosome 7 open reading frame 67".
6. "Archived copy". Archived from the original on 2009-06-27. Retrieved 2009-05-14.CS1 maint: archived copy as title (link)
7. "GEO Profiles: GDS2697 record".

External links

• Human FAM188B genome location and FAM188B gene details page in the UCSC Genome Browser.