Mycinamicin III 3''-O-methyltransferase
Mycinamicin III 3''-O-methyltransferase (EC 2.1.1.237, MycF) is an enzyme with systematic name S-adenosyl-L-methionine:mycinamicin III 3''-O-methyltransferase.[1] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + mycinamicin III S-adenosyl-L-homocysteine + mycinamicin IV
| Mycinamicin III 3''-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.237 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics.
References
- Li S, Anzai Y, Kinoshita K, Kato F, Sherman DH (May 2009). "Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics". ChemBioChem. 10 (8): 1297–301. doi:10.1002/cbic.200900088. PMC 2861363. PMID 19415708.
External links
- -O-methyltransferase Mycinamicin+III+3-O-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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