NIF3L1

NIF3-like protein 1 is a protein that in humans is encoded by the NIF3L1 gene.[5][6][7][8]

NIF3L1
Identifiers
Aliases	NIF3L1, ALS2CR1, CALS-7, MDS015, NGG1 interacting factor 3 like 1
External IDs	OMIM: 605778 MGI: 1929485 HomoloGene: 5881 GeneCards: NIF3L1
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q33.1 Start 200,889,327 bp[1] End 200,903,938 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C1.3 Start 58,445,151 bp[2] End 58,481,816 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • transcription factor binding • GO:0001948 protein binding • identical protein binding Cellular component • cytoplasm • cell nucleus • mitochondrion Biological process • positive regulation of transcription, DNA-templated • negative regulation of nucleic acid-templated transcription • neuron differentiation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	60491	65102
Ensembl	ENSG00000196290	ENSMUSG00000026036
UniProt	Q9GZT8	Q9EQ80
RefSeq (mRNA)	NM_001136039 NM_001142355 NM_001142356 NM_021824 NM_001369441 NM_001369442 NM_001369443 NM_001369444 NM_001369445	NM_022988
RefSeq (protein)	NP_001129511 NP_001135827 NP_001135828 NP_068596 NP_001356370 NP_001356371 NP_001356372 NP_001356373 NP_001356374	NP_075364
Location (UCSC)	Chr 2: 200.89 – 200.9 Mb	Chr 1: 58.45 – 58.48 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

NIF3L1 has been shown to interact with COPS2.[7]

References

1. GRCh38: Ensembl release 89: ENSG00000196290 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026036 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Tascou S, Uedelhoven J, Dixkens C, Nayernia K, Engel W, Burfeind P (Jan 2001). "Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals". Cytogenetics and Cell Genetics. 90 (3–4): 330–6. doi:10.1159/000056799. PMID 11124544. S2CID 23200951.
6. Hadano S, Yanagisawa Y, Skaug J, Fichter K, Nasir J, Martindale D, Koop BF, Scherer SW, Nicholson DW, Rouleau GA, Ikeda J, Hayden MR (Jan 2001). "Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2". Genomics. 71 (2): 200–13. doi:10.1006/geno.2000.6392. PMID 11161814.
7. Akiyama H, Fujisawa N, Tashiro Y, Takanabe N, Sugiyama A, Tashiro F (Mar 2003). "The role of transcriptional corepressor Nif3l1 in early stage of neural differentiation via cooperation with Trip15/CSN2". The Journal of Biological Chemistry. 278 (12): 10752–62. doi:10.1074/jbc.M209856200. PMID 12522100.
8. "Entrez Gene: NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. pombe)".

Further reading

• Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Tascou S, Kang TW, Trappe R, Engel W, Burfeind P (Sep 2003). "Identification and characterization of NIF3L1 BP1, a novel cytoplasmic interaction partner of the NIF3L1 protein". Biochemical and Biophysical Research Communications. 309 (2): 440–8. doi:10.1016/j.bbrc.2003.07.008. PMID 12951069.
• Merla G, Howald C, Antonarakis SE, Reymond A (Jul 2004). "The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3". Human Molecular Genetics. 13 (14): 1505–14. doi:10.1093/hmg/ddh163. PMID 15163635.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY (May 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.