NIP7

60S ribosome subunit biogenesis protein NIP7 homolog is a protein that in humans is encoded by the NIP7 gene.[5][6]

NIP7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1SQW, 1T5Y
Identifiers
Aliases	NIP7, HSPC031, KD93, CGI-37, nucleolar pre-rRNA processing protein, nucleolar pre-rRNA processing protein NIP7
External IDs	MGI: 1913414 HomoloGene: 56743 GeneCards: NIP7
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q22.1 Start 69,337,996 bp[1] End 69,343,106 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 D3 Start 107,056,877 bp[2] End 107,060,931 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • RNA binding Cellular component • cell nucleus • nucleolus • preribosome, large subunit precursor • cytosol Biological process • ribosome biogenesis • ribosome assembly • ribosomal large subunit biogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51388	66164
Ensembl	ENSG00000132603	ENSMUSG00000031917
UniProt	Q9Y221	Q9CXK8
RefSeq (mRNA)	NM_016101 NM_001199434	NM_001164472 NM_025391
RefSeq (protein)	NP_001186363 NP_057185	NP_001157944 NP_079667
Location (UCSC)	Chr 16: 69.34 – 69.34 Mb	Chr 8: 107.06 – 107.06 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

NIP7 has been shown to interact with NOL8.[5]

References

1. GRCh38: Ensembl release 89: ENSG00000132603 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031917 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T (Feb 2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D". J Biol Chem. 279 (9): 8343–50. doi:10.1074/jbc.M305935200. PMID 14660641.
6. "Entrez Gene: NIP7 nuclear import 7 homolog (S. cerevisiae)".

Further reading

• Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
• Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Chagnon P, Michaud J, Mitchell G, Mercier J, Marion JF, Drouin E, Rasquin-Weber A, Hudson TJ, Richter A (2003). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis". Am. J. Hum. Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.
• Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Liu JF, Wang XQ, Wang ZX, Chen JR, Jiang T, An XM, Chang WR, Liang DC (2005). "Crystal structure of KD93, a novel protein expressed in human hematopoietic stem/progenitor cells". J. Struct. Biol. 148 (3): 370–4. doi:10.1016/j.jsb.2004.06.010. PMID 15522784.
• Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.