Olaf Schneewind

Olaf Schneewind was an American Microbiologist who made important contributions to the study of bacterial cell wall composition and assembly as well as the pathogenesis of the microbial species S. aureus.[1] He was elected to the National Academy of Sciences in 2018.[2] He died May 26, 2019 after a long battle with cancer.[1]

Olaf Schneewind
Born23 June 1961
Died26 May 2019(2019-05-26) (aged 57)
Known forS. aureus pathogenesis
Scientific career
FieldsMicrobiology
InstitutionsThe University of Chicago
Doctoral students

Research career

He joined the faculty of the University of California, Los Angeles in 1992.[2] His first major discovery as an independent investigator was the finding that the surface proteins of gram-positive bacteria are cleaved between the T and G residue in the LPXTG sortase signal by the enzyme sortase (the enzyme was not discovered yet, but was later shown by him to be responsible for the cleavage) in order to be anchored to the cell wall.[3]

References
  1. https://news.uchicago.edu/story/olaf-schneewind-world-renowned-authority-infectious-diseases-1961-2019
  2. http://www.nasonline.org/member-directory/deceased-members/20041867.html
  3. Navarre WW, Schneewind O (1994). "Proteolytic cleavage and cell wall anchoring at the LPXTG motif of surface proteins in gram-positive bacteria". Mol Microbiol. 14 (1): 115–21. doi:10.1111/j.1365-2958.1994.tb01271.x. PMID 7830549.
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