Otis (surname)
Otis is a surname of Greek origin or as a variant spelling of the English name Oates.
- Amos Otis, a professional baseball player
- Bill Otis, professional baseball player
- Elisha Otis, inventor of a safety device for hoisting machinery, who went on to invent the first passenger elevator
- Eliza Ann Otis (1833–1904), poet, journalist, philanthropist
- Elwell Otis, an American general who served in the Philippines during the Spanish-American and Philippine-American wars
- Glenn K. Otis U.S. Army general (retd.)
- Harrison Gray Otis (publisher) (1837–1917), a publisher of the Los Angeles Times
- Harrison Gray Otis (lawyer) (1765–1848), a representative and senator from Massachusetts
- James Otis:
- James Otis, Sr. (1702–1778), American revolutionary politician
- James Otis, Jr. (1725–1783), American revolutionary politician
- James Otis, pen name of James Otis Kaler (1848–1912), American journalist and author of children's literature
- James Otis (San Francisco politician) (1826–1875), mayor of San Francisco, California
- James Otis (actor), American film and television actor
- Johnny Otis, American rhythm and blues musician and impresario
- Samuel Allyne Otis, American politician
- Shuggie Otis, American songwriter, recording artist and multi-instrumentalist
- Todd Otis, American politician
- William Otis, inventor of the steam shovel
- Mercy Otis Warren. American writer
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