POP7

Ribonuclease P protein subunit p20 is an enzyme that in humans is encoded by the POP7 gene.[4][5]

POP7
Identifiers
Aliases	POP7, 0610037N12Rik, RPP2, RPP20, POP7 homolog, ribonuclease P/MRP subunit
External IDs	OMIM: 606113 MGI: 1921347 HomoloGene: 4262 GeneCards: POP7
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q22.1 Start 100,706,121 bp[1] End 100,707,486 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleic acid binding • GO:0001948 protein binding • hydrolase activity • RNA binding • ribonuclease P activity Cellular component • cytoplasm • nucleolus • cell nucleus • nucleolar ribonuclease P complex • nucleoplasm • ribonuclease MRP complex • multimeric ribonuclease P complex Biological process • tRNA processing • RNA phosphodiester bond hydrolysis, endonucleolytic • tRNA 5'-leader removal • RNA phosphodiester bond hydrolysis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10248	74097
Ensembl	ENSG00000172336	ENSMUSG00000029715
UniProt	O75817	Q9DCH2
RefSeq (mRNA)	NM_005837	NM_028753
RefSeq (protein)	NP_005828	NP_083029
Location (UCSC)	Chr 7: 100.71 – 100.71 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000172336 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Jarrous N, Eder PS, Guerrier-Takada C, Hoog C, Altman S (Jun 1998). "Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P". RNA. 4 (4): 407–17. PMC 1369627. PMID 9630247.
5. "Entrez Gene: POP7 processing of precursor 7, ribonuclease P subunit (S. cerevisiae)".

Further reading

• Stolc V, Katz A, Altman S (1998). "Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiae". Proc. Natl. Acad. Sci. U.S.A. 95 (12): 6716–21. doi:10.1073/pnas.95.12.6716. PMC 22609. PMID 9618478.
• Jiang T, Altman S (2001). "Protein-protein interactions with subunits of human nuclear RNase P." Proc. Natl. Acad. Sci. U.S.A. 98 (3): 920–5. doi:10.1073/pnas.021561498. PMC 14685. PMID 11158571.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hua Y, Zhou J (2004). "Rpp20 interacts with SMN and is re-distributed into SMN granules in response to stress". Biochem. Biophys. Res. Commun. 314 (1): 268–76. doi:10.1016/j.bbrc.2003.12.084. PMID 14715275.
• Welting TJ, van Venrooij WJ, Pruijn GJ (2004). "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex". Nucleic Acids Res. 32 (7): 2138–46. doi:10.1093/nar/gkh539. PMC 407822. PMID 15096576.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

External links

• POP7 human gene location in the UCSC Genome Browser.
• POP7 human gene details in the UCSC Genome Browser.