PXK

PX domain containing serine/threonine kinase also known as PXK is a protein which in humans is encoded by the PXK gene.[1][2]

PX domain containing serine/threonine kinase
Identifiers
Symbol	PXK
Alt. symbols	FLJ20335, MONaKA
NCBI gene	54899
HGNC	23326
OMIM	611450
RefSeq	NM_017771
UniProt	Q6ZN39
Other data
Locus	Chr. 3 p21.2
Search for Structures Swiss-model Domains InterPro

Function

PXK binds to the Na⁺/K⁺-ATPase beta-1 (ATP1B1) and beta-3 (ATP1B3) subunits and modulates both Na⁺/K⁺-ATPase enzymatic and ion pump activities.[2]

See also

• PX domain

References

1. "Entrez Gene: PX domain containing serine/threonine kinase".
2. Mao H, Ferguson TS, Cibulsky SM, Holmqvist M, Ding C, Fei H, Levitan IB (August 2005). "MONaKA, a novel modulator of the plasma membrane Na,K-ATPase". J. Neurosci. 25 (35): 7934–43. doi:10.1523/JNEUROSCI.0635-05.2005. PMC 6725465. PMID 16135750.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.