Pyrrocaine

Pyrrocaine is a local anesthetic drug. The cogency of pyrrocaine is equivalent to lidocaine in blocking the motor nerve and sensory. Pyrrocaine was proven to be somewhat harmless compared to lidocaine. No signs of methemoglobinemia was found while observing. It was considered unsafe for acute porphyria treatment. No evidence is found that it is profitly used now.[1]

Pyrrocaine

Names
IUPAC name N-(2,6-Dimethylphenyl)-2-(1-pyrrolidinyl)acetamide
Identifiers
CAS Number	2210-77-7
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1895219
ChemSpider	22776
EC Number	218-642-7
KEGG	D05665
PubChem CID	24361
UNII	9D47L94CPW
CompTox Dashboard (EPA)	DTXSID9046150
InChI InChI=1S/C14H20N2O/c1-11-6-5-7-12(2)14(11)15-13(17)10-16-8-3-4-9-16/h5-7H,3-4,8-10H2,1-2H3,(H,15,17) Key: OYCGKECKIVYHTN-UHFFFAOYSA-N
SMILES Cc1cccc(c1NC(=O)CN2CCCC2)C
Properties
Chemical formula	C14H20N2O
Molar mass	232.327
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

History

In the 1960s it was most of the time used as a nerve blocker dental anesthetic and dentists recommended it due to its fast commencement.[1]

Adverse effects

Pyrrocane has very similar side effects on blood pressure and heart rate compared to lidocaine.[2]

See also

• Lidocaine
• Procaine
• Trimecaine
• Local anesthetic
• List of local anesthetics

References

1. "NCATS Inxight: Drugs". drugs.ncats.io. Retrieved 2018-08-07.
2. Annals of Dentistry. New York Academy of Dentistry. 1983.