RAB14

Ras-related protein Rab-14 is a protein that in humans is encoded by the RAB14 gene.[5][6][7]

RAB14
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Z0F, 4D0G, 4DRZ
Identifiers
Aliases	RAB14, FBP, RAB-14, member RAS oncogene family
External IDs	OMIM: 612673 MGI: 1915615 HomoloGene: 48679 GeneCards: RAB14
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q33.2 Start 121,178,133 bp[1] End 121,223,014 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 B Start 35,180,205 bp[2] End 35,201,120 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleotide binding • GDP binding • GTP binding • myosin V binding • GO:0001948 protein binding • GTPase activity Cellular component • recycling endosome • endosome • late endosome • rough endoplasmic reticulum • nuclear outer membrane-endoplasmic reticulum membrane network • intracellular membrane-bounded organelle • membrane • Golgi membrane • intracellular • lysosomal membrane • trans-Golgi network • phagocytic vesicle • perinuclear region of cytoplasm • Golgi stack • trans-Golgi network transport vesicle • lysosome • extracellular exosome • cytoplasmic vesicle • cytosol • cell membrane • cilium • early endosome membrane • recycling endosome membrane • tertiary granule membrane • early endosome • Golgi apparatus Biological process • embryo development • Golgi to endosome transport • intracellular transport • fibroblast growth factor receptor signaling pathway • phagosome maturation • defense response to bacterium • endocytic recycling • protein transport • vesicle-mediated transport • regulation of protein localization • phosphatidylinositol biosynthetic process • neutrophil degranulation • regulation of endocytosis • transport • intracellular protein transport • Rab protein signal transduction • regulation of embryonic development • phagolysosome assembly involved in apoptotic cell clearance Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51552	68365
Ensembl	ENSG00000119396	ENSMUSG00000026878
UniProt	P61106	Q91V41
RefSeq (mRNA)	NM_016322	NM_026697
RefSeq (protein)	NP_057406	NP_080973
Location (UCSC)	Chr 9: 121.18 – 121.22 Mb	Chr 2: 35.18 – 35.2 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000119396 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026878 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. de Leeuw HP, Koster PM, Calafat J, Janssen H, van Zonneveld AJ, van Mourik JA, Voorberg J (Dec 1998). "Small GTP-binding proteins in human endothelial cells". Br J Haematol. 103 (1): 15–9. doi:10.1046/j.1365-2141.1998.00965.x. PMID 9792283. S2CID 24857520.
6. Junutula JR, De Maziere AM, Peden AA, Ervin KE, Advani RJ, van Dijk SM, Klumperman J, Scheller RH (Apr 2004). "Rab14 is involved in membrane trafficking between the Golgi complex and endosomes". Mol Biol Cell. 15 (5): 2218–29. doi:10.1091/mbc.E03-10-0777. PMC 404017. PMID 15004230.
7. "Entrez Gene: RAB14 RAB14, member RAS oncogene family".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Garin J, Diez R, Kieffer S, et al. (2001). "The phagosome proteome: insight into phagosome functions". J. Cell Biol. 152 (1): 165–80. doi:10.1083/jcb.152.1.165. PMC 2193653. PMID 11149929.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Predic J, Soskic V, Bradley D, Godovac-Zimmermann J (2002). "Monitoring of gene expression by functional proteomics: response of human lung fibroblast cells to stimulation by endothelin-1". Biochemistry. 41 (3): 1070–8. doi:10.1021/bi0117854. PMID 11790131.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.