RAB26

Ras-related protein Rab-26 is a protein that in humans is encoded by the RAB26 gene.[5][6]

RAB26
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2G6B
Identifiers
Aliases	RAB26, V46133, member RAS oncogene family
External IDs	OMIM: 605455 MGI: 2443284 HomoloGene: 25655 GeneCards: RAB26
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 2,140,803 bp[1] End 2,154,165 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 24,527,241 bp[2] End 24,534,210 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleotide binding • GTP binding • GO:0001948 protein binding • GMP binding • GTPase activity Cellular component • intrinsic component of plasma membrane • Golgi membrane • Golgi apparatus • transport vesicle membrane • membrane • cytoplasmic vesicle • endosome • cell membrane • synaptic vesicle • secretory granule membrane • anchored component of synaptic vesicle membrane Biological process • protein transport • exocrine system development • regulated exocytosis • Golgi to plasma membrane protein transport • vesicle docking involved in exocytosis • protein secretion • regulation of exocytosis • intracellular protein transport • Rab protein signal transduction • regulation of protein catabolic process at presynapse, modulating synaptic transmission Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	25837	328778
Ensembl	ENSG00000167964	ENSMUSG00000079657
UniProt	Q9ULW5	Q504M8
RefSeq (mRNA)	NM_001308053 NM_014353	NM_177375
RefSeq (protein)	NP_001294982 NP_055168	NP_796349
Location (UCSC)	Chr 16: 2.14 – 2.15 Mb	Chr 17: 24.53 – 24.53 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000167964 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000079657 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Seki N, Yoshikawa T, Hattori A, Miyajima N, Muramatsu M, Saito T (Oct 2000). "cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP-binding protein on chromosome 16p13.3 region". J Hum Genet. 45 (5): 309–14. doi:10.1007/s100380070023. PMID 11043516.
6. "Entrez Gene: RAB26 RAB26, member RAS oncogene family".

Further reading

• Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j.1471-4159.2006.03836.x. PMC 2239266. PMID 16696853.
• Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94. doi:10.1038/nature03187. PMID 15616553.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Yoshie S, Imai A, Nashida T, Shimomura H (2000). "Expression, characterization, and localization of Rab26, a low molecular weight GTP-binding protein, in the rat parotid gland". Histochem. Cell Biol. 113 (4): 259–63. doi:10.1007/s004180000130. PMID 10857477. S2CID 39587270.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.