RAB40A

Ras-related protein Rab-40A is a protein that in humans is encoded by the RAB40A gene.[3][4]

RAB40A
Identifiers
Aliases	RAB40A, RAR2, RAR2A, member RAS oncogene family
External IDs	HomoloGene: 89095 GeneCards: RAB40A
Gene location (Human) Chr. X chromosome (human)[1] Band Xq22.2 Start 103,499,130 bp[1] End 103,519,489 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleotide binding • GTP binding • GTPase activity Cellular component • membrane • endosome • cell membrane • synaptic vesicle • secretory granule membrane • Golgi membrane Biological process • GO:0007243 intracellular signal transduction • protein ubiquitination • vesicle docking involved in exocytosis • protein secretion • protein localization to plasma membrane • regulation of exocytosis • intracellular protein transport • Rab protein signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	142684	n/a
Ensembl	ENSG00000172476	n/a
UniProt	Q8WXH6	n/a
RefSeq (mRNA)	NM_080879	n/a
RefSeq (protein)	NP_543155	n/a
Location (UCSC)	Chr X: 103.5 – 103.52 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

References

1. GRCh38: Ensembl release 89: ENSG00000172476 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
4. "Entrez Gene: RAB40A RAB40A, member RAS oncogene family".

Further reading

• Kile BT, Schulman BA, Alexander WS, et al. (2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem. Sci. 27 (5): 235–41. doi:10.1016/S0968-0004(02)02085-6. PMID 12076535.
• Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.
• Fukuda M, Kuroda TS, Mikoshiba K (2002). "Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport". J. Biol. Chem. 277 (14): 12432–6. doi:10.1074/jbc.C200005200. PMID 11856727.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Itoh T, Satoh M, Kanno E, Fukuda M (2006). "Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity". Genes Cells. 11 (9): 1023–37. doi:10.1111/j.1365-2443.2006.00997.x. PMID 16923123.