Ring forming reaction

A ring forming reaction or ring-closing reaction in organic chemistry is a general term for a variety of reactions that introduce one or more rings into a molecule. A heterocycle forming reaction is such a reaction that introduces a new heterocycle.[1][2] Important classes of ring forming reactions include annulations[3] and cycloadditions.

Named ring forming reactions

Named ring forming reactions include (not exhaustive):

• Azide-alkyne Huisgen cycloaddition
• Bischler–Napieralski reaction
• Bucherer carbazole synthesis
• Danheiser annulation
• Diels–Alder reaction
• Fischer indole synthesis
• Larock indole synthesis
• Paal–Knorr synthesis
• Pictet–Spengler reaction
• Pomeranz–Fritsch reaction
• Ring-closing metathesis
• Robinson annulation
• Skraup reaction

References

1. IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version:  (1995) "Heterocyclic compounds". doi:10.1351/goldbook.H02798
2. Katritzky, A. R.; Pozharskii, A. F. (2000). Handbook of Heterocyclic Chemistry (2nd ed.). Academic Press. ISBN 0080429882.
3. IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version:  (2006–) "annulation". doi:10.1351/goldbook.A00367

Further reading

• Michael B. Smith & Jerry March, 2007, "March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure," 6th Ed., New York, NY, USA:Wiley & Sons, ISBN 0470084944, see , accessed 19 June 2015.
• László Kürti & Barbara Czakó, 2005, "Strategic Applications of Named Reactions in Organic Synthesis: Background and Detailed Mechanisms, Amsterdam, NH, NLD:Elsevier Academic Press, 2005ISBN 0124297854, see , accessed 19 June 2015.