SEPT14

Septin 14 is a protein that in humans is encoded by the SEPT14 gene.[4]

SEPTIN14
Identifiers
Aliases	SEPTIN14, septin 14, SEPT14
External IDs	OMIM: 612140 MGI: 1921472 HomoloGene: 87501 GeneCards: SEPTIN14
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p11.2 Start 55,793,540 bp[1] End 55,862,755 bp[1]
Gene ontology Molecular function • nucleotide binding • GTP binding • GO:0001948 protein binding • GTPase activity • GO:0032947 molecular adaptor activity Cellular component • cytoplasm • cytoskeleton • septin ring • microtubule cytoskeleton • septin complex • septin filament array Biological process • cell cycle • cell division • mitotic cytokinesis • septin ring assembly • cilium morphogenesis • cytoskeleton-dependent cytokinesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	346288	74222
Ensembl	ENSG00000154997	n/a
UniProt	Q6ZU15	Q9DA97
RefSeq (mRNA)	NM_207366	NM_028826
RefSeq (protein)	NP_997249	NP_083102
Location (UCSC)	Chr 7: 55.79 – 55.86 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Function

SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions.

References

1. GRCh38: Ensembl release 89: ENSG00000154997 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: Septin 14".

Further reading

• Peterson EA, Kalikin LM, Steels JD, Estey MP, Trimble WS, Petty EM (November 2007). "Characterization of a SEPT9 interacting protein, SEPT14, a novel testis-specific septin". Mammalian Genome. 18 (11): 796–807. doi:10.1007/s00335-007-9065-x. PMID 17922164. S2CID 9906543.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.