SMU1

WD40 repeat-containing protein SMU1 is a protein that in humans is encoded by the SMU1 gene.[4][5][6]

SMU1
Identifiers
Aliases	SMU1, BWD, SMU-1, fSAP57, smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans), DNA replication regulator and spliceosomal factor, DNA replication regulator and spliceosomal factor, SMU1 DNA replication regulator and spliceosomal factor
External IDs	OMIM: 617811 MGI: 1915546 HomoloGene: 10079 GeneCards: SMU1
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9p21.1 Start 33,041,765 bp[1] End 33,076,674 bp[1]
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cytoplasm • nuclear speck • cell nucleus • U2-type precatalytic spliceosome Biological process • regulation of alternative mRNA splicing, via spliceosome • mRNA processing • RNA splicing • mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55234	74255
Ensembl	ENSG00000122692	ENSMUSG00000028409
UniProt	Q2TAY7	Q3UKJ7
RefSeq (mRNA)	NM_018225	NM_021535
RefSeq (protein)	NP_060695 NP_060695.2	NP_067510
Location (UCSC)	Chr 9: 33.04 – 33.08 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000122692 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Spike CA, Shaw JE, Herman RK (Jul 2001). "Analysis of smu-1, a gene that regulates the alternative splicing of unc-52 pre-mRNA in Caenorhabditis elegans". Mol Cell Biol. 21 (15): 4985–95. doi:10.1128/MCB.21.15.4985-4995.2001. PMC 87225. PMID 11438655.
5. Di Benedetto AJ, Klick Stoddard J, Glavan BJ (Jun 2001). "Cloning and molecular characterization of a novel gene encoding a WD-repeat protein expressed in restricted areas of adult rat brain". Gene. 271 (1): 21–31. doi:10.1016/S0378-1119(01)00483-8. PMID 11410362.
6. "Entrez Gene: SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ficarro SB, Salomon AR, Brill LM, et al. (2005). "Automated immobilized metal affinity chromatography/nano-liquid chromatography/electrospray ionization mass spectrometry platform for profiling protein phosphorylation sites". Rapid Commun. Mass Spectrom. 19 (1): 57–71. doi:10.1002/rcm.1746. PMID 15570572.
• Higa LA, Wu M, Ye T, et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation". Nat. Cell Biol. 8 (11): 1277–83. doi:10.1038/ncb1490. hdl:10397/34293. PMID 17041588. S2CID 22180568.