SPATA2

Spermatogenesis-associated protein 2 is a protein that in humans is encoded by the SPATA2 gene.[5]

SPATA2
Identifiers
Aliases	SPATA2, PD1, PPP1R145, tamo, spermatogenesis associated 2
External IDs	OMIM: 607662 MGI: 2146885 HomoloGene: 4407 GeneCards: SPATA2
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q13.13 Start 49,903,391 bp[1] End 49,915,529 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 H3 Start 167,481,133 bp[2] End 167,492,887 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • molecular function Cellular component • cytoplasm • cell nucleus • fibrillar center Biological process • multicellular organism development • cell differentiation • spermatogenesis • regulation of tumor necrosis factor-mediated signaling pathway • regulation of inflammatory response • regulation of necroptotic process • protein K63-linked deubiquitination • protein linear deubiquitination • programmed cell death Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9825	263876
Ensembl	ENSG00000158480	ENSMUSG00000047030
UniProt	Q9UM82	Q8K004
RefSeq (mRNA)	NM_001135773 NM_006038	NM_170756 NM_001356523
RefSeq (protein)	NP_001129245 NP_006029	NP_001343452 NP_739562
Location (UCSC)	Chr 20: 49.9 – 49.92 Mb	Chr 2: 167.48 – 167.49 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000158480 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047030 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: SPATA2 spermatogenesis associated 2".

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
• Graziotto R, Foresta C, Scannapieco P, et al. (1999). "cDNA cloning and characterization of PD1: a novel human testicular protein with different expressions in various testiculopathies". Exp. Cell Res. 248 (2): 620–6. doi:10.1006/excr.1999.4449. PMID 10222154.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Liliana Slongo M, Zotti L, Onisto M (2003). "Cloning and characterization of the promoter region of human spata2 (spermatogenesis-associated protein 2) gene". Biochim. Biophys. Acta. 1625 (2): 192–6. doi:10.1016/s0167-4781(02)00594-8. PMID 12531478.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.