SPATA5

Spermatogenesis-associated protein 5 is a protein that in humans is encoded by the SPATA5 gene.[5][6]

SPATA5
Identifiers
Aliases	SPATA5, AFG2, SPAF, EHLMRS, spermatogenesis associated 5
External IDs	OMIM: 613940 MGI: 1927170 HomoloGene: 56920 GeneCards: SPATA5
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q28.1 Start 122,923,078 bp[1] End 123,319,433 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 B Start 37,419,896 bp[2] End 37,579,096 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleotide binding • ATP binding • ATPase activity • hydrolase activity Cellular component • cytoplasm • mitochondrion Biological process • multicellular organism development • cell differentiation • brain development • spermatogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	166378	57815
Ensembl	ENSG00000145375	ENSMUSG00000027722
UniProt	Q8NB90	Q3UMC0
RefSeq (mRNA)	NM_145207 NM_001317799 NM_001345856	NM_001163511 NM_021343 NM_001310473
RefSeq (protein)	NP_001304728 NP_001332785 NP_660208	NP_001156983 NP_001297402 NP_067318
Location (UCSC)	Chr 4: 122.92 – 123.32 Mb	Chr 3: 37.42 – 37.58 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000145375 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027722 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Katoh Y, Katoh M (Feb 2006). "FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells". International Journal of Molecular Medicine. 17 (3): 529–32. doi:10.3892/ijmm.17.3.529. PMID 16465403.
6. "Entrez Gene: SPATA5 spermatogenesis associated 5".

Further reading

• Liu Y, Black J, Kisiel N, Kulesz-Martin MF (2000). "SPAF, a new AAA-protein specific to early spermatogenesis and malignant conversion". Oncogene. 19 (12): 1579–88. doi:10.1038/sj.onc.1203442. PMID 10734318.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences of the United States of America. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nature Genetics. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.