Sarcotoxin

Sarcotoxins are a group of antibacterial peptides present in the flesh fly belonging to the genus Sarcophaga. The proteins are present in the haemolymph of the fresh fly. The first protein, called sarcotoxin 1A, was discovered in 1983 from Sarcophaga peregrina by Masayuki Okada and Shunji Natori at the University of Tokyo, Japan.[1][2]

The name Sarcotoxin is derived from the peptide's discovery in Sarcophaga flies, and so antibacterial compounds were given the name Sarcotoxin and an identifying number or letter. However many Sarcotoxins are homologues of Cecropins or Attacins, and are not unique to Sarcophaga flies.[3][4]

References
  1. Iwai, H.; Nakajima, Y.; Natori, S.; Arata, Y.; Shimada, I. (Oct 1993). "Solution conformation of an antibacterial peptide, sarcotoxin IA, as determined by 1H-NMR". Eur J Biochem. 217 (2): 639–44. doi:10.1111/j.1432-1033.1993.tb18287.x. PMID 8223606.
  2. Okada M, Natori S (1984). "Mode of action of a bactericidal protein induced in the haemolymph of Sarcophaga peregrina (flesh-fly) larvae". Biochem J. 222 (1): 119–124. PMC 1144151. PMID 6383355.
  3. "Sarcotoxin II-3 precursor - Sarcophaga peregrina (Flesh fly)". www.uniprot.org. Retrieved 2021-02-02.
  4. "Sarcotoxin-1A precursor - Sarcophaga peregrina (Flesh fly)". www.uniprot.org. Retrieved 2021-02-02.
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