StarBase (database)
StarBase is a database for decoding miRNA-mRNA, miRNA-lncRNA, miRNA-sncRNA, miRNA-circRNA, miRNA-pseudogene, protein-lncRNA, protein-ncRNA, protein-mRNA interactions and ceRNA networks from CLIP-Seq (HITS-CLIP, PAR-CLIP, iCLIP, CLASH) and degradome sequencing data.[1][2] starBase provides miRFunction and ceRNAFunction web tools to predict the function of ncRNAs (miRNAs, lncRNAs, pseudogenes) and protein-coding genes from the miRNA and ceRNA regulatory networks.
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| Content | |
| Description | microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data. |
| Contact | |
| Research center | Sun Yat-sen University |
| Laboratory | Key Laboratory of Gene Engineering of the Ministry of Education |
| Authors | Jian-Hua Yang |
| Primary citation | Yang & al. (2011)[1] |
| Release date | 2010 |
| Access | |
| Website | http://starbase.sysu.edu.cn/ |
starBase also deverloped Pan-Cancer Analysis Platform to decipher Pan-Cancer Analysis Networks of lncRNAs, miRNAs, ceRNAs and RNA-binding proteins (RBPs) by mining clinical and expression profiles of 14 cancer types (>6000 samples) from The Cancer Genome Atlas (TCGA) Data Portal.
References
- Yang, Jian-Hua; Li Jun-Hao; Shao Peng; Zhou Hui; Chen Yue-Qin; Qu Liang-Hu (Jan 2011). "starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data". Nucleic Acids Res. England. 39 (Database issue): D202-9. doi:10.1093/nar/gkq1056. PMC 3013664. PMID 21037263.
- Li, JH; Liu, S; Zhou, H; Qu, LH; Yang, JH (Dec 1, 2013). "starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data". Nucleic Acids Research. 42 (1): D92-7. doi:10.1093/nar/gkt1248. PMC 3964941. PMID 24297251.
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